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How to get fromSouth Carolina to Key Largoby plane, shuttle, train, bus, car, or taxi

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There are 10 ways to get from South Carolina to Key Largo by plane, shuttle, train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Miami International Airport, shuttle

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA)plane plane GSP - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4h 26m
    $211–578

  2. Drive  644.5 mi

    cheapest
    1. Drive from Charleston to Key Largocar car 644.5 mi
    10h 58m
    $118–170

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    17h 6m
    $394–607

  4. Drive, bus, taxi, train via Jacksonville

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Miami Airport Stationbus bus
    6. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    19h 46m

  5. Taxi to Charlotte Douglas International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Miami International Airport (MIA)plane plane CLT - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4h 51m
    $311–926

  6. Fly Greenville–Spartanburg International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane GSP - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 1m
    $291–638

  7. Taxi to Charlotte Douglas International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CLT - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 20m
    $311–576

  8. Fly Charleston International Airport to Miami International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 3m
    $594–1,134

  9. Fly Charleston International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    6h 31m
    $524–1,254

  10. Drive, bus, taxi, train

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Miami Amtrak Stationtrain train
    5. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    19h 44m

Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA) flights

Calendar42Weekly Planes
Duration3h 40mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from South Carolina to Key Largo.ExpandLaunch map view
  • Distance: 709.7 mi
  • Duration: 4h 26m

What companies run services between South Carolina, USA and Key Largo, FL, USA?

There is no direct connection from South Carolina to Key Largo. However, you can take the taxi to Greenville–Spartanburg International Airport (GSP) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take a vehicle from Charleston to Key Largo Bus Stop via Charleston Amtrak Station, Hollywood Amtrak Station, Hollywood Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 17h 6m.

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