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How to get fromSouth Carolina to Key Largoby plane, shuttle, train, bus, car, or taxi

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There are 9 ways to get from South Carolina to Key Largo by plane, shuttle, train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Miami International Airport, shuttle

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA)plane plane GSP - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4h 30m
    $226–628

  2. Drive 644.5 mi

    cheapest
    1. Drive from Charleston to Key Largocar car 644.5 mi
    10h 58m
    $118–170

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    17h 6m
    $268–507

  4. Drive, bus

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the bus from Savannah Bus Station to Ft Lauderdale Broward Park & Ridebus bus
    4. Take the bus from Ft Lauderdale Broward Park & Ride to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    17h 29m

  5. Fly Greenville–Spartanburg International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane GSP - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    4h 57m
    $301–998

  6. Taxi to Charlotte Douglas International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Miami International Airport (MIA)plane plane CLT - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4h 53m
    $311–606

  7. Taxi to Charlotte Douglas International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CLT - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 18m
    $276–576

  8. Fly Charleston International Airport to Miami International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 2m
    $604–1,134

  9. Fly Charleston International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    6h 33m
    $294–1,254

Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA) flights

Calendar54Weekly Planes
Duration3h 49mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Key Largo.ExpandLaunch map view
  • Distance: 709.7 mi
  • Duration: 4h 30m

What companies run services between South Carolina, USA and Key Largo, FL, USA?

There is no direct connection from South Carolina to Key Largo. However, you can take the taxi to Greenville–Spartanburg International Airport (GSP) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take a vehicle from Charleston to Key Largo Bus Stop via Charleston Amtrak Station, Hollywood Amtrak Station, Hollywood Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 17h 6m.

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