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How to get fromSouth Carolina to Key Westby taxi, plane, train, bus, or car

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There are 8 ways to get from South Carolina to Key West by taxi, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Charlotte Douglas International Airport, fly

    best
    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane plane CLT - EYW
    2h 52m
    $172–519

  2. Fly from Greenville–Spartanburg International Airport

    cheapest
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW)plane plane GSP - EYW
    4h 18m
    $132–461

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    21h 42m
    $266–516

  4. Drive, bus

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the bus from Savannah Bus Station to Ft Lauderdale Broward Park & Ridebus bus
    4. Take the bus from Ft Lauderdale Broward Park & Ride to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    22h 6m

  5. Drive 741.6 mi

    1. Drive from Charleston to Key Westcar car 741.6 mi
    13h 14m
    $136–196

  6. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Key West International Airport (EYW)plane plane AVL - EYW
    3h 10m
    $214–507

  7. Fly from Columbia

    1. Fly from Columbia (CAE) to Key West International Airport (EYW)plane plane CAE - EYW
    5h 31m
    $152–764

  8. Fly from Charleston International Airport

    1. Fly from Charleston International Airport (CHS) to Key West International Airport (EYW)plane plane CHS - EYW
    5h 56m
    $285–517

Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW) flights

Calendar55Weekly Planes
Duration3h 59mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Key West.ExpandLaunch map view
  • Distance: 767.9 mi
  • Duration: 2h 52m

What companies run services between South Carolina, USA and Key West, FL, USA?

Delta, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW) every 4 hours.

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