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How to get fromSouth Carolina to Missouriby taxi, plane, car, bus, train, or train (Amtrak)

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There are 8 ways to get from South Carolina to Missouri by taxi, plane, car, bus, train, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Charlotte Douglas International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    3h 14m
    $194–749

  2. Fly Charleston International Airport to Lambert–St. Louis International Airport

    cheapest
    1. Fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL)plane plane CHS - STL
    4h 50m
    $107–557

  3. Drive, bus, taxi, train

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Fayetteville Amtrak Stationtrain train
    5. Take the bus from Fayetteville Bus Station to Atlanta Bus Stationbus bus
    6. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    7. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    34h 22m

  4. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    37h 45m
    $571–1,176

  5. Drive 1,087.5 mi

    1. Drive from Charleston to Kansas Citycar car 1,087.5 mi
    18h 53m
    $199–287

  6. Taxi to Charlotte Douglas International Airport, fly to Springfield-Branson National Airport

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Springfield-Branson National Airport (SGF)plane plane CLT - SGF
    3h 8m
    $187–596

  7. Taxi to Charlotte Douglas International Airport, fly to Columbia Regional Airport

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia Regional Airport (COU)plane plane CLT - COU
    3h 6m
    $221–631

  8. Taxi to Charlotte Douglas International Airport, fly to Kansas City

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Kansas City (MCI)plane plane CLT - MCI
    4h 40m
    $231–896

Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) flights

Calendar56Weekly Planes
Duration2h 58mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Missouri.ExpandLaunch map view
  • Distance: 614.9 mi
  • Duration: 3h 14m

What companies run services between South Carolina, USA and Missouri, USA?

You can take a vehicle from Charleston to Metro Center via Charleston Amtrak Station, Petersburg Amtrak Station, Chicago Union Station, Kansas City, and Union Station in around 37h 45m. Alternatively, Southwest Airlines, Delta, and American Airlines fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL) every 4 hours.

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