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How to get fromSouth Carolina to Port Saint Lucieby taxi, plane, train, bus, or car

Find Transport to Port Saint Lucie

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There are 5 ways to get from South Carolina to Port Saint Lucie by taxi, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly to Vero Beach Municipal Airport

    best
    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Vero Beach Municipal Airport (VRB)plane plane CLT - VRB
    3. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    3h 24m
    $266–756

  2. Drive 472.2 mi

    cheapest
    1. Drive from Charleston to Port Saint Luciecar car 472.2 mi
    8h 2m
    $87–125

  3. Train, bus via Buenaventura Lakes

    1. Take the train from Charleston Amtrak Station to Kissimmee Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus Orlando to Miami
    14h 45m
    $156–316

  4. Taxi, fly to Melbourne International Airport, bus

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Melbourne International Airport (MLB)plane plane CLT - MLB
    3. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    4. Take the bus from Sebastian to Port St Luciebus bus
    6h 32m
    $247–659

  5. Train, bus

    1. Take the train from Charleston Amtrak Station to West Palm Beach Amtrak Stationtrain train Silver Meteor
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus 95
    15h 36m
    $218–440

South Carolina to Port Saint Lucie by bus and train

Calendar7Weekly Services
Duration14h 45mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Port Saint Lucie.ExpandLaunch map view
  • Distance: 578.2 mi
  • Duration: 3h 24m

What companies run services between South Carolina, USA and Port Saint Lucie, FL, USA?

There is no direct connection from South Carolina to Port Saint Lucie. However, you can take the taxi to Charlotte-Airport-CLT airport, fly to Vero Beach Municipal Airport (VRB), then take the taxi to Port Saint Lucie. Alternatively, you can take a bus from Mary St / Meeting St to Fort Pierce via N. Charleston SuperStop, North Charleston Transit Center, Charleston Amtrak Station, Kissimmee Amtrak Station, Pleasant St & Neptune Rd, Osceola Pkwy Walmart, and Kissimmee -1471 East Osceola Parkway in around 14h 45m.

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