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How to get fromSouth Carolina to Sanibel Islandby plane, car, bus, taxi, or train

Find Transport to Sanibel Island

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There are 8 ways to get from South Carolina to Sanibel Island by plane, car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Ft. Myers (RSW)plane plane GSP - RSW
    2h 40m
    $206–683

  2. Drive 547.9 mi

    cheapest
    1. Drive from Charleston to Sanibel Islandcar car 547.9 mi
    10h 4m
    $100–145

  3. Drive, bus, taxi, train via Wildwood

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    6. Take the bus from Wildwood to Fort Myersbus bus
    17h 12m

  4. Train, bus, taxi

    1. Take the train from Charleston Amtrak Station to Fort Lauderdale Amtrak Stationtrain train
    2. Take the bus from Fort Lauderdale Airport to Naples, FLbus bus
    3. Take the taxi from Naples, FL to Sanibel Islandtaxi taxi
    17h 55m
    $377–671

  5. Taxi to Charlotte Douglas International Airport, fly

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Ft. Myers (RSW)plane plane CLT - RSW
    3h 4m
    $236–731

  6. Line 11 bus to Charleston International Airport, fly

    1. Take the bus from N. Charleston SuperStop on Rivers Ave to Centre Pointe Dr / Tanger Outlet Blvdbus bus
    2. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    4h 22m
    $154–549

  7. Train, bus (Amtrak)

    1. Take the train from Charleston Amtrak Station to Orlandotrain train Silver Meteor
    2. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus Amtrak Thruway Connecting Service
    17h 56m
    $259–459

  8. Drive, bus, taxi, train

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    6. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    18h 50m

Greenville–Spartanburg International Airport (GSP) to Ft. Myers (RSW) flights

Calendar45Weekly Planes
Duration3h 56mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Sanibel Island.ExpandLaunch map view
  • Distance: 615.9 mi
  • Duration: 2h 40m

What companies run services between South Carolina, USA and Sanibel Island, FL, USA?

Breeze Airways, Delta, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Ft. Myers (RSW) every 4 hours.

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