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How to get fromSouth Padre Island to Key Westby taxi, plane, bus, ferry, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from South Padre Island to Key West by taxi, plane, bus, ferry, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Rio Grande Valley International Airport, fly

    best
    1. Take the taxi from South Padre Island to Rio Grande Valley International Airport (HRL)taxi taxi
    2. Fly from Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW)plane plane HRL - EYW
    8h 32m
    $194–490

  2. Fly from Brownsville-South Padre Island International Airport

    cheapest
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW)plane plane BRO - EYW
    7h 27m
    $103–393

  3. Taxi, bus, ferry

    1. Take the taxi from South Padre Island to Brownsville Bus Stationtaxi taxi
    2. Take the bus from Brownsville Bus Station to Houston - Harrisburg Blvdbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    34h 13m
    $495–593

  4. Drive  1,691.8 mi

    1. Drive from South Padre Island to Key Westcar car 1,691.8 mi
    30h 20m
    $299–432

  5. Bus to Mcallen Miller International Airport, fly

    1. Take the bus from La Plaza at Brownsville to McAllen Central Stationbus bus
    2. Fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW)plane plane MFE - EYW
    9h 46m
    $117–417

  6. Bus, ferry

    1. Take the bus from La Plaza at Brownsville to Houston Bus Stationbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    36h 49m
    $427–550

  7. Bus

    1. Take the bus from La Plaza at Brownsville to Houston Bus Stationbus bus
    2. Take the bus from Houston Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    47h 7m
    $337–539

Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW) flights

Calendar9Weekly Planes
Duration9h 8mAverage Duration
Ticket$75Cheapest Price
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Comparing Your Travel Options

Map of how to get from South Padre Island to Key West.ExpandLaunch map view
  • Distance: 1,040 mi
  • Duration: 8h 32m

What companies run services between South Padre Island, TX, USA and Key West, FL, USA?

United Airlines and American Airlines fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW) once daily. Alternatively, you can take a vehicle from South Padre Island to N Roosevelt & 3rd Street via Las Palmas Port Isabel, La Plaza at Brownsville, Houston Bus Station, Tallahassee, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 47h 7m.

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