There are 9 ways to get from South Philadelphia to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Buffalo Niagara International Airport
best- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
4h 2m$94–606Drive 345.4 mi
cheapest- Drive from South Philadelphia to Buffalocar 345.4 mi
7h 14m$63–91Bus
- Take the bus from Philadelphia Bus Station to Newark Penn Stationbus Greyhound US0421 / ...
- Take the bus from Newark Penn Station to Buffalobus FlixBus 2686 / ...
10h 25m$72–120Train (Amtrak)
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain Empire Service / ...
10h 59m$131–856Fly Philadelphia International Airport to Rochester, bus
- Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane PHL - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 28m$142–844Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
4h 53m$92–518Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
4h 58m$100–1,161Train to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
6h 27m$120–1,216Bus via Scranton (Greyhound)
- Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus Greyhound US0340s
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
12h 10m$63–106
South Philadelphia to Buffalo by bus
Comparing Your Travel Options
The cheapest way to get from South Philadelphia to Buffalo is to bus via Scranton which costs $60 - $110 and takes 12h 10m.
The fastest way to get from South Philadelphia to Buffalo is to fly which takes 4h 2m and costs $90 - $650.
No, there is no direct bus from South Philadelphia station to Buffalo. However, there are services departing from Philadelphia Bus Station and arriving at Buffalo via Newark Penn Station. The journey, including transfers, takes approximately 10h 25m.
No, there is no direct train from South Philadelphia station to Buffalo. However, there are services departing from 30th Street Station and arriving at Buffalo via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 10h 59m.
The distance between South Philadelphia and Buffalo is 297 miles. The road distance is 347.4 miles.
The best way to get from South Philadelphia to Buffalo without a car is to bus which takes 10h 25m and costs $70 - $120.
It takes approximately 4h 2m to get from South Philadelphia to Buffalo, including transfers.
South Philadelphia to Buffalo bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
South Philadelphia to Buffalo train services, operated by Amtrak, depart from 30th Street Station.
The best way to get from South Philadelphia to Buffalo is to fly which takes 4h 2m and costs $90 - $650. Alternatively, you can bus, which costs $70 - $120 and takes 10h 25m, you could also train, which costs $130 - $900 and takes 10h 59m.
What companies run services between South Philadelphia, PA, USA and Buffalo, NY, USA?
American Airlines and United Airlines fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Philadelphia Bus Station to Buffalo via Newark Penn Station in around 10h 25m.
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $90–600
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 45m
- When
- Saturday
- Estimated price
- $100–700
Flights from Philadelphia International Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $110–800
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $90–600
Flights from Laguardia Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $23–55
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $110–260
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $20–45
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $27–60
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $23–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $12–20
- Website
- Greyhound
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $60–100
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–19
- Website
- Greyhound
Bus from Philadelphia Bus Station to Scranton Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $22–40
- Website
- Greyhound
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
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Booking & Getting There
South Philadelphia to Buffalo bus services, operated by Greyhound USA, arrive at Newark Penn Station.
South Philadelphia to Buffalo train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between South Philadelphia to Buffalo is 347 miles. It takes approximately 7h 14m to drive from South Philadelphia to Buffalo.
Book your South Philadelphia to Buffalo train tickets online with Omio.
Book your South Philadelphia to Buffalo bus tickets online with Omio and FlixBus.
There are 256+ hotels available in Buffalo.







