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How to get fromSouth Philadelphia to Buffaloby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

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There are 9 ways to get from South Philadelphia to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    4h 5m
    $98–631

  2. Bus via Scranton (Greyhound)

    cheapest
    1. Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus bus Greyhound US0340s
    2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
    12h 10m
    $56–114

  3. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Newark to Buffalobus bus Adt N816 / ...
    10h
    $66–261

  4. Train (Amtrak)

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    10h 59m
    $141–866

  5. Drive 345.4 mi

    1. Drive from South Philadelphia to Buffalocar car 345.4 mi
    7h 14m
    $63–91

  6. Fly Philadelphia International Airport to Rochester, bus

    1. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 28m
    $141–795

  7. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 51m
    $92–536

  8. Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    4h 58m
    $104–1,186

  9. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    6h 28m
    $119–1,241

South Philadelphia to Buffalo by bus

Calendar25Weekly Buses
Duration10hAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from South Philadelphia to Buffalo.ExpandLaunch map view
  • Distance: 294.7 mi
  • Duration: 4h 5m

What companies run services between South Philadelphia, PA, USA and Buffalo, NY, USA?

American Airlines and United Airlines fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Buffalo via Newark in around 10h.

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