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How to get fromSouth Philadelphia to Buffaloby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

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There are 9 ways to get from South Philadelphia to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    4h
    $138–882

  2. Drive  345.4 mi

    cheapest
    1. Drive from South Philadelphia to Buffalocar car 345.4 mi
    7h 15m
    $59–86

  3. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    10h 25m
    $78–131

  4. Train (Amtrak)

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    10h 59m
    $261–966

  5. Fly Philadelphia International Airport to Rochester, bus

    1. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 21m
    $112–596

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 55m
    $128–644

  7. Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    5h 3m
    $124–1,286

  8. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    5h 38m
    $100–1,063

  9. Bus via Scranton (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus bus Greyhound US0340s
    2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
    12h 10m
    $71–114

South Philadelphia to Buffalo by bus

Calendar43Weekly Buses
Duration10h 25mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from South Philadelphia to Buffalo.ExpandLaunch map view
  • Distance: 294.7 mi
  • Duration: 4h

What companies run services between South Philadelphia, PA, USA and Buffalo, NY, USA?

American Airlines and United Airlines fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a bus from Philadelphia Bus Station to Buffalo via Newark Penn Station in around 10h 25m.

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Train operators
Bus operators

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