There are 5 ways to get from South Station to Buffalo Depew Station by plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
2h 48m$92–516Bus (Greyhound)
cheapest- Take the bus from Boston to Buffalobus Greyhound US0171
12h 18m$76–139Train (Amtrak)
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
11h 39m$150–330Drive 444.7 mi
- Drive from South Station to Buffalo Depew Stationcar 444.7 mi
7h 53m$82–118Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus FlixBus 2685 / ...
14h 55m$93–204
South Station to Buffalo Depew Station by train (Amtrak)
Questions & Answers
The cheapest way to get from South Station to Buffalo Depew Station is to bus which costs $75 - $140 and takes 12h 18m.
The fastest way to get from South Station to Buffalo Depew Station is to fly which takes 2h 48m and costs $90 - $550.
No, there is no direct bus from South Station to Buffalo Depew Station. However, there are services departing from Boston and arriving at Walden Avenue & 2929 Walden Avenue via Ellicott Street & MTC Static and Walden Avenue & Thruway Transit Center. The journey, including transfers, takes approximately 12h 18m.
Yes, there is a direct train departing from Boston and arriving at Buffalo Depew Station station. Services depart once daily, and operate every day. The journey takes approximately 11h 39m.
The distance between South Station and Buffalo Depew Station is 403 miles. The road distance is 447.3 miles.
The best way to get from South Station to Buffalo Depew Station without a car is to train which takes 11h 39m and costs $150 - $330.
It takes approximately 2h 48m to get from South Station to Buffalo Depew Station, including transfers.
South Station to Buffalo Depew Station bus services, operated by Greyhound USA, depart from Boston station.
South Station to Buffalo Depew Station train services, operated by Amtrak, depart from Boston station.
The best way to get from South Station to Buffalo Depew Station is to fly which takes 2h 48m and costs $90 - $550. Alternatively, you can train, which costs $150 - $330 and takes 11h 39m, you could also bus, which costs $75 - $140 and takes 12h 18m.
What companies run services between South Station, MA, USA and Buffalo Depew Station, NY, USA?
American Airlines, JetBlue Airways, and three other airlines fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $150–330 and the journey takes 11h 39m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $80–500
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $90–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–500
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $150–330
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Twice daily
- Estimated price
- $70–140
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 6 times a week
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- 3 times a day
- Estimated price
- $26–45
- Schedules at
- Flixbus USA
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More Questions & Answers
South Station to Buffalo Depew Station bus services, operated by Greyhound USA, arrive at Buffalo station.
South Station to Buffalo Depew Station train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between South Station to Buffalo Depew Station is 447 miles. It takes approximately 7h 53m to drive from South Station to Buffalo Depew Station.
Book your South Station to Buffalo Depew Station train tickets online with Omio.
There are 227+ hotels available in Buffalo Depew Station.