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How to get fromSouthborough to Hyannisby train, bus, car, or bus (Greyhound)

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There are 6 ways to get from Southborough to Hyannis by train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Southborough to South Stationtrain train Framingham/Worcester Line
    2. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus Boston
    4h 44m
    $22–52

  2. Train

    cheapest
    1. Take the train from Southborough to South Stationtrain train Framingham/Worcester Line
    2. Take the train from South Station to Hyannistrain train CapeFLYER
    5h 39m
    $12–34

  3. Drive 89.6 mi

    1. Drive from Southborough to Hyanniscar car 89.6 mi
    1h 51m
    $17–24

  4. Line 07 bus, train, bus

    1. Take the bus from Downtown Southborough to Banana Lot/Intermodal Centerbus bus 07
    2. Take the train from Framingham to South Stationtrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    4h 52m
    $32–46

  5. Line 07 bus, train, bus via Boston

    1. Take the bus from Downtown Southborough to Banana Lot/Intermodal Centerbus bus 07
    2. Take the train from Framingham to South Stationtrain train
    3. Take the bus from Boston to Hyannisbus bus
    4h 59m
    $20–52

  6. Line 07 bus, bus

    1. Take the bus from Downtown Southborough to Banana Lot/Intermodal Centerbus bus 07
    2. Take the bus from Framingham to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    5h 10m
    $32–44

Southborough to Hyannis by bus and train

Calendar63Weekly Services
Duration4h 44mAverage Duration
Ticket$22Cheapest Price
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Questions & Answers

Map of how to get from Southborough to Hyannis.ExpandLaunch map view
  • Distance: 104 mi
  • Duration: 4h 44m

What companies run services between Southborough, MA, USA and Hyannis, MA, USA?

You can take a bus from Southborough at St Marks to Hyannis via Southborough MBTA Station, Southborough, and South Station in around 5h 39m. Alternatively, you can take a bus from Downtown Southborough to Hyannis Transportation Center via Framingham, Boston, and Boston South Buses in around 5h 10m.

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