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How to get fromSouthborough to Ithacaby bus (Greyhound, Flixbus), train, bus, car, or plane

Find Transport to Ithaca

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There are 8 ways to get from Southborough to Ithaca by bus (Greyhound, Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Framingham to Springfield Union Stationbus bus Greyhound US0270s
    2. Take the bus from Springfield Union Station to Ithacabus bus FlixBus 2691
    10h 12m
    $58–104

  2. Drive 307.4 mi

    cheapest
    1. Drive from Southborough to Ithacacar car 307.4 mi
    5h 46m
    $57–81

  3. Train, bus

    1. Take the train from Framingham Amtrak to Utica Amtrak Stationtrain train Lake Shore Limited
    2. Take the bus from Utica Bus Stop to Ithacabus bus FlixBus 2691
    12h 17m
    $104–212

  4. Train, fly to Ithaca Tompkins Regional Airport

    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH)plane plane BOS - ITH
    8h 55m
    $64–352

  5. Bus via New York

    1. Take the bus from Worcester to New Yorkbus bus Ppb 5725 / ...
    2. Take the bus from New York to Ithacabus bus Adt N806
    11h 35m
    $74–246

  6. Train, fly to Rochester, bus

    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester to Ithacabus bus
    8h 19m
    $138–650

  7. Train, fly to Syracuse Hancock International Airport, bus

    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    8h 22m
    $112–616

  8. Train, fly to Buffalo Niagara International Airport, bus

    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Ithacabus bus
    9h 44m
    $118–562

Southborough to Ithaca by bus

Calendar6Weekly Buses
Duration10h 12mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

Map of how to get from Southborough to Ithaca.ExpandLaunch map view
  • Distance: 375.3 mi
  • Duration: 10h 12m

What companies run services between Southborough, MA, USA and Ithaca, NY, USA?

You can take a bus from Downtown Southborough to Ithaca via Framingham and Springfield Union Station in around 10h 12m.

Airlines
Train operators
Bus operators

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