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How to get fromSpartanburg to Buffaloby plane, train, bus, bus (Greyhound), car, or train (Amtrak)

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There are 6 ways to get from Spartanburg to Buffalo by plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF)plane plane GSP - BUF
    5h 6m
    $197–895

  2. Drive 708 mi

    cheapest
    1. Drive from Spartanburg to Buffalocar car 708 mi
    12h 37m
    $130–187

  3. Train, bus

    1. Take the train from Spartanburg Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    24h 45m
    $290–571

  4. Bus

    1. Take the bus from Spartanburg to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    27h 35m
    $200–378

  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Spartanburg to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    6h 18m
    $166–825

  6. Train (Amtrak)

    1. Take the train from Spartanburg Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    25h 13m
    $360–731

Spartanburg to Buffalo by train and bus

Calendar7Weekly Services
Duration24h 45mAverage Duration
Ticket$290Cheapest Price
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Questions & Answers

Map of how to get from Spartanburg to Buffalo.ExpandLaunch map view
  • Distance: 619.5 mi
  • Duration: 5h 6m

What companies run services between Spartanburg, SC, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Spartanburg to Buffalo via Atlanta Bus Station and Cleveland Bus Station in around 27h 35m.

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