There are 5 ways to get from Spartanburg to Florence by bus (Greyhound), train (Amtrak), car, train, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Spartanburg to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
6h 18m$46–79Drive 148.8 mi
cheapest- Drive from Spartanburg to Florencecar 148.8 mi
3h 36m$28–40Train (Amtrak)
- Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain
- Take the train from Charlotte Amtrak Station to Selma Stationtrain
- Take the train from Selma Station to Florence Stationtrain
10h 43m$124–280Train, fly
- Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Florence Regional Airport (FLO)plane CLT - FLO
5h 23m$80–399Train, bus
- Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
7h 8m$46–93
Spartanburg to Florence by train (Amtrak)
Questions & Answers
The cheapest way to get from Spartanburg to Florence is to drive which costs $27 - $40 and takes 3h 36m.
The fastest way to get from Spartanburg to Florence is to drive which takes 3h 36m and costs $27 - $40.
No, there is no direct bus from Spartanburg to Florence station. However, there are services departing from Spartanburg and arriving at Florence Bus Station via Charlotte Bus Station and Camden. The journey, including transfers, takes approximately 6h 18m.
No, there is no direct train from Spartanburg station to Florence station. However, there are services departing from Spartanburg Station and arriving at Florence Station via Charlotte Amtrak Station and Selma Station. The journey, including transfers, takes approximately 10h 43m.
The distance between Spartanburg and Florence is 216 miles. The road distance is 149.7 miles.
The best way to get from Spartanburg to Florence without a car is to bus which takes 6h 18m and costs $45 - $80.
It takes approximately 6h 18m to get from Spartanburg to Florence, including transfers.
Spartanburg to Florence bus services, operated by Greyhound USA, depart from Spartanburg station.
Spartanburg to Florence train services, operated by Amtrak, depart from Spartanburg Station.
The best way to get from Spartanburg to Florence is to bus which takes 6h 18m and costs $45 - $80. Alternatively, you can train, which costs $120 - $280 and takes 10h 43m.
What companies run services between Spartanburg, SC, USA and Florence, SC, USA?
You can take a vehicle from Spartanburg to Florence Bus Station via Spartanburg, Charlotte Bus Station, and Camden in around 6h 18m. Alternatively, you can take a train from Spartanburg Station to Florence Station via Charlotte Amtrak Station and Selma Station in around 10h 43m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Florence Regional Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $40–330
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Spartanburg Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 2m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
Train from Charlotte Amtrak Station to Selma Station
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- Amtrak
Train from Selma Station to Florence Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Amtrak
Train from Spartanburg Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 2m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
Train from Spartanburg Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 2m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Spartanburg to Charlotte Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $7–14
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $7–14
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Spartanburg to Florence bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Spartanburg to Florence train services, operated by Amtrak, arrive at Charlotte Amtrak Station.
Yes, the driving distance between Spartanburg to Florence is 150 miles. It takes approximately 3h 36m to drive from Spartanburg to Florence.
Book your Spartanburg to Florence train tickets online with Omio.
Book your Spartanburg to Florence bus tickets online with Omio.
There are 47+ hotels available in Florence.







