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How to get fromSpartanburg to Indianaby plane, train, bus (Greyhound, Flixbus), bus, or car

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There are 8 ways to get from Spartanburg to Indiana by plane, train, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 39m
    $125–440

  2. Drive 493.9 mi

    cheapest
    1. Drive from Spartanburg to Indianapoliscar car 493.9 mi
    9h 34m
    $91–131

  3. Bus

    1. Take the bus from Spartanburg to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    16h 55m
    $112–196

  4. Train, bus

    1. Take the train from Spartanburg Station to High Pointtrain train
    2. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    20h 56m
    $140–326

  5. Train to Charlotte Douglas International Airport, fly to South Bend

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    6h 15m
    $152–719

  6. Train to Charlotte Douglas International Airport, fly to Evansville

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Evansville (EVV)plane plane CLT - EVV
    6h 12m
    $106–464

  7. Train to Charlotte Douglas International Airport, fly to Indianapolis

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    6h 56m
    $119–603

  8. Train to Charlotte Douglas International Airport, fly to Fort Wayne International Airport

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Fort Wayne International Airport (FWA)plane plane CLT - FWA
    6h 27m
    $127–496

Spartanburg to Indiana by train and bus

Calendar3Weekly Services
Duration20h 56mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Spartanburg to Indiana.ExpandLaunch map view
  • Distance: 645.1 mi
  • Duration: 4h 39m

What companies run services between Spartanburg, SC, USA and Indiana, USA?

You can take a vehicle from Spartanburg to Indianapolis via Spartanburg and Atlanta Bus Station in around 16h 55m.

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