Rome2Rio

How to get fromSpartanburg to Indianaby plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Flixbus)

Find Transport to Indiana

See all options

There are 8 ways to get from Spartanburg to Indiana by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 32m
    $116–381

  2. Drive  493.9 mi

    cheapest
    1. Drive from Spartanburg to Indianapoliscar car 493.9 mi
    9h 34m
    $91–131

  3. Bus

    1. Take the bus from Spartanburg to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    16h 45m
    $132–206

  4. Train (Amtrak)

    1. Take the train from Spartanburg Station to Charlottesvilletrain train Crescent
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    24h 13m
    $517–837

  5. Train to Charlotte Douglas International Airport, fly to Evansville

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Evansville (EVV)plane plane CLT - EVV
    6h 7m
    $127–464

  6. Train to Charlotte Douglas International Airport, fly to Indianapolis

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    6h 50m
    $135–623

  7. Train to Charlotte Douglas International Airport, fly to Fort Wayne International Airport

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Fort Wayne International Airport (FWA)plane plane CLT - FWA
    6h 19m
    $143–496

  8. Bus via Sandy Springs

    1. Take the bus from Servicios Zapata - Spartanburg to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    17h 38m
    $139–216

Spartanburg to Indiana by train (Amtrak)

Calendar3Weekly Trains
Duration24h 13mAverage Duration
Ticket$517Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Spartanburg to Indiana.ExpandLaunch map view
  • Distance: 645 mi
  • Duration: 4h 32m

What companies run services between Spartanburg, SC, USA and Indiana, USA?

You can take a vehicle from Spartanburg to Indianapolis via Spartanburg and Atlanta Bus Station in around 16h 45m. Alternatively, you can take a train from Spartanburg Station to Indianapolis via Charlottesville in around 24h 13m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There