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How to get fromSpartanburg to Indianapolisby plane, bus, train (Amtrak), car, or bus (Greyhound)

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There are 6 ways to get from Spartanburg to Indianapolis by plane, bus, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND)plane plane GSP - IND
    4h 53m
    $168–718

  2. Drive 493.9 mi

    cheapest
    1. Drive from Spartanburg to Indianapoliscar car 493.9 mi
    9h 34m
    $91–131

  3. Bus

    1. Take the bus from Spartanburg to Atlantabus bus Acb 1152
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    15h 20m

  4. Train (Amtrak)

    1. Take the train from Spartanburg Station to Charlottesvilletrain train Crescent
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    24h 13m
    $301–622

  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Spartanburg to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    6h 21m

  6. Bus via Indianapolis, Illinois St (Greyhound Bus Station)

    1. Take the bus from Spartanburg to Atlantabus bus Acb 1152
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus Greyhound US0100
    16h 20m

Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND) flights

Calendar124Weekly Planes
Duration4h 23mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Spartanburg to Indianapolis.ExpandLaunch map view
  • Distance: 435.6 mi
  • Duration: 4h 53m

What companies run services between Spartanburg, SC, USA and Indianapolis, IN, USA?

Delta, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Spartanburg to Indianapolis via Atlanta Bus Station in around 15h 20m.

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