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How to get fromSpartanburg to Key Westby plane, bus, shuttle, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Spartanburg to Key West by plane, bus, shuttle, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW)plane plane GSP - EYW
    4h 28m
    $147–479

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Spartanburg to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Key West International Airport (EYW)plane plane AVL - EYW
    3h 12m
    $86–357

  3. Bus, shuttle

    1. Take the bus from Servicios Zapata - Spartanburg to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    25h 38m
    $346–580

  4. Bus, train

    1. Take the bus from Spartanburg to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    27h 11m
    $297–592

  5. Drive 879.7 mi

    1. Drive from Spartanburg to Key Westcar car 879.7 mi
    15h 17m
    $161–232

  6. Bus

    1. Take the bus from Spartanburg to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    25h 40m
    $174–328

  7. Train, bus

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Take the train from Charlotte Amtrak Station to Carytrain train
    3. Take the train from Cary to West Palm Beach Amtrak Stationtrain train
    4. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    36h 36m
    $392–815

Spartanburg to Key West by train, bus, and foot

Calendar7Weekly Services
Duration36h 36mAverage Duration
Ticket$392Cheapest Price
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Questions & Answers

Map of how to get from Spartanburg to Key West.ExpandLaunch map view
  • Distance: 735.9 mi
  • Duration: 4h 28m

What companies run services between Spartanburg, SC, USA and Key West, FL, USA?

Delta, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a vehicle from Spartanburg to N Roosevelt & 3rd Street via Spartanburg, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 40m.

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