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How to get fromSpartanburg to Lancasterby plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 6 ways to get from Spartanburg to Lancaster by plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Philadelphia International Airport, train

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Philadelphia International Airport (PHL)plane plane GSP - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    7h 29m
    $186–729

  2. Drive 533.2 mi

    cheapest
    1. Drive from Spartanburg to Lancastercar car 533.2 mi
    10h 40m
    $98–141

  3. Bus

    1. Take the bus from Spartanburg to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    17h 56m
    $109–206

  4. Train (Amtrak)

    1. Take the train from Spartanburg Station to 30th Street Stationtrain train Crescent
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    18h 5m
    $214–445

  5. Train to Charlotte Douglas International Airport, fly to Harrisburg International Airport

    1. Take the train from Spartanburg Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Harrisburg International Airport (MDT)plane plane CLT - MDT
    9h 51m
    $101–480

  6. Fly Greenville–Spartanburg International Airport to Baltimore-Washington International Airport, train

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Baltimore-Washington International Airport (BWI)plane plane GSP - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    8h 39m
    $192–1,268

Spartanburg to Lancaster by train and bus (Amtrak)

Calendar7Weekly Services
Duration18h 5mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

Map of how to get from Spartanburg to Lancaster.ExpandLaunch map view
  • Distance: 649.2 mi
  • Duration: 7h 29m

What companies run services between Spartanburg, SC, USA and Lancaster, PA, USA?

You can take a vehicle from Spartanburg to W. Chestnut & Water St. via Spartanburg, Charlotte Bus Station, Baltimore Downtown Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 17h 56m. Alternatively, you can take a train from Spartanburg Station to W. Chestnut & Water St. via 30th Street Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 18h 5m.

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