There are 8 ways to get from Speyer to Lyon by train (TGV), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mannheim, Hauptbahnhof to Offenburg Bahnhoftrain 12 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
7h 50m€125–359Bus
cheapest- Take the bus from Karlsruhe central train station to Lyonbus FlixBus N1135 / ...
10h 10m€53–104Drive 568.1 km
- Drive from Speyer to Lyoncar 568.1 km
6h 6m€89–128Train to Frankfurt, fly to Lyon–Saint Exupéry Airport
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
5h 21m€139–335Train via Karlsruhe
- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain S3
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
8h 18m€133–272Train via Karlsruhe #2
- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain S3
- Take the train from Karlsruhe Hauptbahnhof to Appenweier Bahnhoftrain Re2 / ...
- Take the train from Strasbourg Bahnhof to Lyon Part Dieutrain 84
8h 28m€138–292Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Speyer, Hbf/ZOB to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Offenburg Bahnhoftrain
- Take the train from Offenburg Bahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane SXB - LYS
6h 5m€152–488Train to Frankfurt, fly to Geneva International Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
- Take the train from Bellegarde to Lyon Part Dieutrain
8h 4m€169–421
Speyer to Lyon by train
Questions & Answers
The cheapest way to get from Speyer to Lyon is to bus which costs €50 - €110 and takes 10h 10m.
The fastest way to get from Speyer to Lyon is to train and fly which takes 5h 21m and costs €130 - €340.
No, there is no direct bus from Speyer to Lyon. However, there are services departing from Speyer, Domplatz and arriving at Lyon via Karlsruhe central train station. The journey, including transfers, takes approximately 10h 10m.
No, there is no direct train from Speyer to Lyon. However, there are services departing from Speyer, Hbf/ZOB and arriving at Lyon Part Dieu via Mannheim, Hauptbahnhof, Offenburg Bahnhof and Strasbourg. The journey, including transfers, takes approximately 7h 50m.
The distance between Speyer and Lyon is 685 km. The road distance is 568.1 km.
The best way to get from Speyer to Lyon without a car is to train which takes 7h 50m and costs €120 - €360.
It takes approximately 7h 50m to get from Speyer to Lyon, including transfers.
Speyer to Lyon bus services, operated by FlixBus, depart from Karlsruhe central train station.
Speyer to Lyon train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Speyer to Lyon is to train which takes 7h 50m and costs €120 - €360. Alternatively, you can bus, which costs €50 - €110 and takes 10h 10m.
What companies run services between Speyer, Germany and Lyon, France?
You can take a train from Speyer, Hbf/ZOB to Lyon Part Dieu via Mannheim, Hauptbahnhof, Offenburg Bahnhof, Strasbourg Bahnhof, and Strasbourg in around 7h 50m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Lyon every 4 hours. Tickets cost €45–80 and the journey takes 8h. BlaBlaCar Bus also services this route 5 times a day.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €55–320
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €100–470
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €150–650
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €100–470
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- €100–500
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €130–550
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €110–470
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Wednesday
- Estimated price
- €650–1,100
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- €23–100
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–60
- Website
- https://int.bahn.de/en
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 46 min
- Frequency
- Every 4 hours
- Estimated price
- €15–65
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- €23–100
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–60
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 1h 19m
- Frequency
- Once daily
- Estimated price
- €14–30
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 1h 19m
- Frequency
- Once daily
- Estimated price
- €14–30
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 1h 24m
- Frequency
- Twice daily
- Estimated price
- €28–50
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 1h 24m
- Frequency
- Twice daily
- Estimated price
- €28–50
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 3h 58m
- Frequency
- Every 3 hours
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 3h 58m
- Frequency
- Every 3 hours
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Train from Offenburg Bahnhof to Strasbourg Bahnhof
- Ave. Duration
- 25 min
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.sncf-connect.com/en-en
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 11m
- Frequency
- Twice daily
- Estimated price
- €27–45
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €21–40
- Website
- https://int.bahn.de/en
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €21–40
- Website
- https://int.bahn.de/en
Train from Karlsruhe Hauptbahnhof to Appenweier Bahnhof
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €14–25
- Website
- https://int.bahn.de/en
Train from Speyer, Hbf/ZOB to Mannheim, Hauptbahnhof
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- €5–9
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- suewex.de
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- suewex.de
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Strasbourg Bahnhof to Lyon Part Dieu
- Ave. Duration
- 3h 43m
- Frequency
- Once daily
- Estimated price
- €85–170
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- €22–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +49 7821 2702-0
- [email protected]
- Website
- sweg.de
Train from Offenburg Bahnhof to Strasbourg Bahnhof
- Ave. Duration
- 29 min
- Frequency
- Hourly
- Estimated price
- €29–80
- Schedules at
- sweg.de
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Karlsruhe central train station to Lyon
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Karlsruhe central train station to Lyon
- Ave. Duration
- 9h 30m
- Frequency
- 5 times a day
- Estimated price
- €50–90
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Speyer to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Speyer to Lyon train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Offenburg Bahnhof station.
Yes, the driving distance between Speyer to Lyon is 568 km. It takes approximately 6h 6m to drive from Speyer to Lyon.
Book your Speyer to Lyon train tickets online with Omio.
There are 4133+ hotels available in Lyon.










































