There are 8 ways to get from Speyer to Lyon by train (TGV), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Lyon Perrachetrain Tgv
8h 22m€124–212Bus
cheapest- Take the bus from Mannheim central bus station to Lyonbus N7720 / ...
10h 37m€50–93Drive 568.1 km
- Drive from Speyer to Lyoncar 568.1 km
6h 6m€108–156Train to Frankfurt, fly to Lyon–Saint Exupéry Airport
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
5h 42m€136–365Train via Lyon Part Dieu
- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
8h 29m€114–202Train, bus
- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Lausannetrain
- Take the bus from Lausanne Bus Station to Lyon Perrache Bus Stationbus
11h 22m€104–245Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhoftrain
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane SXB - LYS
6h 36m€141–391Train to Frankfurt, fly to Geneva International Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
- Take the train from Bellegarde to Lyon Part Dieutrain
8h 27m€155–359
Speyer to Lyon by train
Comparing Your Travel Options
The cheapest way to get from Speyer to Lyon is to bus which costs €50 - €95 and takes 10h 37m.
The fastest way to get from Speyer to Lyon is to train and fly which takes 5h 42m and costs €130 - €370.
No, there is no direct bus from Speyer to Lyon. However, there are services departing from Speyer, Hbf/ZOB and arriving at Lyon via Mannheim central bus station. The journey, including transfers, takes approximately 10h 37m.
No, there is no direct train from Speyer to Lyon. However, there are services departing from Speyer, Hbf/ZOB and arriving at Lyon Perrache via Karlsruhe Hauptbahnhof and Strasbourg. The journey, including transfers, takes approximately 8h 22m.
The distance between Speyer and Lyon is 686 km. The road distance is 568.1 km.
The best way to get from Speyer to Lyon without a car is to train which takes 8h 22m and costs €120 - €220.
It takes approximately 8h 22m to get from Speyer to Lyon, including transfers.
Speyer to Lyon bus services, operated by FlixBus, depart from Mannheim central bus station.
Speyer to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), depart from Speyer, Hbf/ZOB station.
The best way to get from Speyer to Lyon is to train which takes 8h 22m and costs €120 - €220. Alternatively, you can bus, which costs €50 - €95 and takes 10h 37m.
What companies run services between Speyer, Germany and Lyon, France?
You can take a train from Speyer, Hbf/ZOB to Lyon Perrache via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 8h 22m. Alternatively, FlixBus operates a bus from Mannheim central bus station to Lyon 3 times a day. Tickets cost €55–85 and the journey takes 8h 50m. BlaBlaCar Bus also services this route once daily.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–500
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €80–240
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €100–230
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- €100–450
- Website
- airbus.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–230
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday to Saturday
- Estimated price
- €170–500
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €150–440
- Website
- brusselsairlines.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €75–290
Flights from Frankfurt to Geneva International Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €150–300
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Wednesday
- Estimated price
- €650–1,300
- Website
- airfrance.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €55–340
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 43m
- Frequency
- 5 times a week
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Speyer, Hbf/ZOB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Lyon Perrache
- Ave. Duration
- 4h 5m
- Frequency
- Once a week
- Estimated price
- €100–160
- Website
- TGV inOui
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 12m
- Frequency
- 3 times a day
- Estimated price
- €100–150
- Website
- TGV inOui
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 20m
- Frequency
- 6 times a week
- Estimated price
- €90–150
- Website
- Oui.SNCF
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 12m
- Frequency
- 6 times a week
- Estimated price
- €22–40
- Website
- Oui.SNCF
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- 6 times a week
- Estimated price
- €60–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Lausanne
- Ave. Duration
- 2h 24m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Once a week
- Estimated price
- €50
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mannheim central bus station to Lyon
- Ave. Duration
- 8h 50m
- Frequency
- 3 times a day
- Estimated price
- €55–85
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mannheim central bus station to Lyon
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €50–80
- Website
- BlaBlaCar Bus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Lausanne Bus Station to Lyon Perrache Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice a week
- Estimated price
- €13–22
- Website
- RegioJet
Want to know more about travelling around France
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Booking & Getting There
Speyer to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Speyer to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Yes, the driving distance between Speyer to Lyon is 568 km. It takes approximately 6h 6m to drive from Speyer to Lyon.
Book your Speyer to Lyon train tickets online with Omio.
There are 3894+ hotels available in Lyon.















































