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How to get fromSpeyer to Pragueby train, plane, bus, night train, or car

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There are 10 ways to get from Speyer to Prague by train, plane, bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly to Václav Havel Airport Prague

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    5h 9m
    Kč 1,668–4,013

  2. Train, bus

    cheapest
    1. Take the train from Speyer, Hbf/ZOB to Frankfurttrain train Re4
    2. Take the bus from Frankfurt Central Train Station to Prague Wilsonova Bus Stationbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    8h 51m
    Kč 1,278–2,018

  3. Train, bus via Dresden

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Dresden Hauptbahnhoftrain train 50
    3. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus N60 / ...
    8h 47m
    Kč 2,750–6,993

  4. Night train

    1. Take the nighttrain from Mannheim Hbf to Praha Hlavni Nadrazinighttrain night train En
    11h 7m
    Kč 3,420–6,033

  5. Train to Stuttgart Airport, fly to Václav Havel Airport Prague

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Václav Havel Airport Prague (PRG)plane plane STR - PRG
    6h 59m
    Kč 3,053–8,963

  6. Train to Frankfurt, fly to Dresden Airport, bus

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    3. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus
    6h 28m
    Kč 3,695–8,943

  7. Train to Munich International Airport, fly to Václav Havel Airport Prague

    1. Take the train from Mannheim, Hauptbahnhof to München Hbftrain train
    2. Fly from Munich International Airport (MUC) to Václav Havel Airport Prague (PRG)plane plane MUC - PRG
    6h 38m
    Kč 3,768–9,913

  8. Bus

    1. Take the bus from Speyer, Domplatz to Heidelberg, Hauptbahnhofbus bus 717
    2. Take the bus from Heidelberg to Prague - Florenc Main Bus Terminalbus bus BlaBlaCar Bus
    9h 41m

  9. Train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    3. Take the train from Nürnberg Hbf to Schwandorftrain train
    4. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    9h 49m
    Kč 3,030–8,733

  10. Drive  502.1 km

    1. Drive from Speyer to Praguecar car 502.1 km
    4h 21m
    Kč 2,289–3,306

Speyer to Prague by train and bus

Calendar69Weekly Services
Duration8h 47mAverage Duration
TicketKč 2,750Cheapest Price
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Comparing Your Travel Options

Map of how to get from Speyer to Prague.ExpandLaunch map view
  • Distance: 516.5 km
  • Duration: 5h 9m

What companies run services between Speyer, Germany and Prague, Czechia?

ÖBB operates a vehicle from Mannheim Hbf to Praha Hlavni Nadrazi 3 times a day. Tickets cost Kč 3,300–5,500 and the journey takes 9h 43m. Alternatively, you can take a bus from Speyer, Domplatz to Prague - Florenc Main Bus Terminal via Heidelberg, Hauptbahnhof and Heidelberg in around 9h 41m.

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