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How to get fromSpeyer to Pragueby bus, train, night train, car, or plane

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There are 10 ways to get from Speyer to Prague by bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Mannheim central bus station to Praguebus bus N1309 / ...
    8h 27m
    Kč 1,104–1,900

  2. Train, bus

    cheapest
    1. Take the train from Speyer, Hbf/ZOB to Heidelberg, Hauptbahnhoftrain train S3 / ...
    2. Take the bus from Heidelberg to Prague - Florenc Main Bus Terminalbus bus BlaBlaCar Bus
    8h 39m
    Kč 1,060–1,751

  3. Train, bus via Dresden

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Dresden Hauptbahnhoftrain train 50
    3. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus N60 / ...
    8h 32m
    Kč 2,473–5,296

  4. Night train

    1. Take the nighttrain from Mannheim Hbf to Praha Hlavni Nadrazinighttrain night train En
    11h 7m
    Kč 3,363–5,586

  5. Drive  502.1 km

    1. Drive from Speyer to Praguecar car 502.1 km
    4h 21m
    Kč 2,255–3,258

  6. Train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    3. Take the train from Nürnberg Hbf to Schwandorftrain train
    4. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    9h 49m
    Kč 2,573–5,196

  7. Train to Frankfurt, fly to Václav Havel Airport Prague

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    5h 7m
    Kč 1,611–3,566

  8. Train to Stuttgart Airport, fly to Václav Havel Airport Prague

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Václav Havel Airport Prague (PRG)plane plane STR - PRG
    6h 59m
    Kč 2,951–8,141

  9. Train to Frankfurt, fly to Dresden Airport, bus

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    3. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus
    6h 11m
    Kč 3,493–8,206

  10. Train to Munich International Airport, fly to Václav Havel Airport Prague

    1. Take the train from Mannheim, Hauptbahnhof to München Hbftrain train
    2. Fly from Munich International Airport (MUC) to Václav Havel Airport Prague (PRG)plane plane MUC - PRG
    6h 38m
    Kč 3,621–8,606

Speyer to Prague by bus and train

Calendar40Weekly Services
Duration8h 27mAverage Duration
TicketKč 1,104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Speyer to Prague.ExpandLaunch map view
  • Distance: 538.6 km
  • Duration: 8h 27m

What companies run services between Speyer, Germany and Prague, Czechia?

FlixBus operates a bus from Mannheim central bus station to Prague every 4 hours. Tickets cost Kč 1,100–1,700 and the journey takes 6h 40m. Alternatively, ÖBB operates a vehicle from Mannheim Hbf to Praha Hlavni Nadrazi 3 times a day. Tickets cost Kč 3,300–5,500 and the journey takes 9h 43m.

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