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How to get fromSpokane to Florenceby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 7 ways to get from Spokane to Florence by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Spokane International Airport (GEG) to Florence Regional Airport (FLO)plane plane GEG - FLO
    12h 56m
    $132–568

  2. Bus

    1. Take the bus from Spokane Station to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 15h
    $445–755

  3. Train, bus

    1. Take the train from Spokane to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    2d 19h
    $779–1,754

  4. Drive  2,579 mi

    1. Drive from Spokane to Florencecar car 2,579 mi
    43h 1m
    $471–680

  5. Fly to Fayetteville Municipal Airport, train

    1. Fly from Spokane International Airport (GEG) to Fayetteville Municipal Airport (FAY)plane plane GEG - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    11h 22m
    $169–624

  6. Fly to Charleston International Airport, train

    1. Fly from Spokane International Airport (GEG) to Charleston International Airport (CHS)plane plane GEG - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    12h 35m
    $180–714

  7. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Spokane International Airport (GEG) to Charlotte Douglas International Airport (CLT)plane plane GEG - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    13h 4m
    $195–793

Spokane to Florence by bus

Calendar7Weekly Buses
Duration2d 15hAverage Duration
Ticket$445Cheapest Price
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Comparing Your Travel Options

Map of how to get from Spokane to Florence.ExpandLaunch map view
  • Distance: 2,163.8 mi
  • Duration: 12h 56m

What companies run services between Spokane, WA, USA and Florence, SC, USA?

American Airlines, Delta, and three other airlines fly from Spokane International Airport (GEG) to Florence Regional Airport (FLO) every 4 hours. Alternatively, you can take a bus from Spokane Station to Florence Bus Station via Pasco Bus Stop, Denver Union Station, St Louis Bus Station, and Atlanta Bus Station in around 2d 15h.

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Want to know more about travelling around United States

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