There are 9 ways to get from Spoleto to Palermo by train, plane, car, ferry, train (Trenitalia), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Fiumicino International Airport, fly
best- Take the train from Spoleto to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane FCO - PMO
5h 30m€38–160Drive, ferry
- Drive from Spoleto to Naples Beverellocar
- Take the ferry from Naples Beverello to Port of Palermoferry
11h 24m€79–140Train (Trenitalia)
- Take the train from Spoleto to Roma Terminitrain 4153 / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
14h 13m€104–199Bus
- Take the bus from Palombara to Roma, Autostazione Tiburtinabus E433
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus Autoservizi Salemi S201
16h 10m€50–76Train to Florence Peretola Airport, fly
- Take the train from Spoleto to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
6h 20m€68–258Train, bus to Perugia Sant'Egidio Airport, fly
- Take the train from Spoleto to Assisitrain
- Take the bus from Assisi to Aeroporto Internazionale dell'Umbriabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
5h 16m€59–266Train, train to Pisa International Airport, fly
- Take the train from Spoleto to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
7h 36m€75–296Train, ferry
- Take the train from Spoleto to Roma Terminitrain
- Take the train from Roma Termini to Napoli Centraletrain Fr
- Take the ferry from Naples Beverello to Port of Palermoferry
11h 42m€69–158Train, bus
- Take the train from Spoleto to Roma Tiburtinatrain 4153 / ...
- Take the bus from Roma, Autostazione Tiburtina to Palermobus N592
16h 26m€98–153
Spoleto to Palermo by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Spoleto to Palermo is to bus which costs €50 - €80 and takes 16h 10m.
The fastest way to get from Spoleto to Palermo is to train and bus and fly which takes 5h 16m and costs €55 - €270.
No, there is no direct bus from Spoleto to Palermo. However, there are services departing from Via Nursina and arriving at Palermo Terminal Bus via Palombara and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 16h 10m.
No, there is no direct train from Spoleto to Palermo. However, there are services departing from Spoleto and arriving at Palermo Centrale via Roma Termini. The journey, including transfers, takes approximately 14h 13m.
The distance between Spoleto and Palermo is 594 km.
The best way to get from Spoleto to Palermo without a car is to train which takes 14h 13m and costs €100 - €200.
It takes approximately 5h 30m to get from Spoleto to Palermo, including transfers.
Spoleto to Palermo bus services, operated by Busitalia Umbria, depart from Palombara station.
Spoleto to Palermo train services, operated by Trenitalia, depart from Spoleto station.
The best way to get from Spoleto to Palermo is to train which takes 14h 13m and costs €100 - €200. Alternatively, you can bus, which costs €50 - €80 and takes 16h 10m.
What companies run services between Spoleto, Italy and Palermo, Italy?
You can take a train from Spoleto to Palermo Centrale via Roma Termini in around 14h 13m. Alternatively, you can take a bus from Via Nursina to Palermo Terminal Bus via Palombara and Roma, Autostazione Tiburtina in around 16h 10m.
- Website
- ryanair.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €18–110
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €30–250
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Pisa International Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 20m
- When
- Sunday
- Estimated price
- €35–200
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €45–190
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- €85–180
- Website
- flyulendo.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €18–110
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €16–65
- Website
- volotea.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €45–190
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €18–130
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €85–180
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €16–120
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 41m
- Frequency
- Every 2 hours
- Estimated price
- €14–21
- Website
- Trenitalia
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 41m
- Frequency
- Every 2 hours
- Estimated price
- €14–21
- Website
- Trenitalia
Train from Spoleto to Assisi
- Ave. Duration
- 30 min
- Frequency
- Every 4 hours
- Estimated price
- €4–7
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 41m
- Frequency
- Every 2 hours
- Estimated price
- €14–21
- Website
- Trenitalia
Train from Roma Termini to Napoli Centrale
- Ave. Duration
- 3h
- Frequency
- Every 4 hours
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Spoleto to Roma Tiburtina
- Ave. Duration
- 1h 23m
- Frequency
- Every 2 hours
- Estimated price
- €14–20
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a day
- Estimated price
- €13–25
- Website
- Trenitalia Intercity
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a day
- Estimated price
- €13–25
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Spoleto to Firenze S.M.N.
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €22–45
- Website
- Trenitalia Intercity
Train from Spoleto to Assisi
- Ave. Duration
- 31 min
- Frequency
- Twice daily
- Estimated price
- €4–8
- Website
- Trenitalia Intercity
Train from Spoleto to Firenze S.M.N.
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €22–45
- Website
- Trenitalia Intercity
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a day
- Estimated price
- €13–25
- Website
- Trenitalia Intercity
Train from Roma Termini to Napoli Centrale
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €24–45
- Website
- Trenitalia Intercity
Train from Spoleto to Roma Tiburtina
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- €13–24
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Spoleto to Roma Termini
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Roma Termini to Napoli Centrale
- Ave. Duration
- 1h 13m
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Napoli Centrale
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- €26–45
- Website
- Italo Treno
- Phone
- +39 06 44101
- [email protected]
- Website
- fsbusitalia.it
Bus from Palombara to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 17m
- Frequency
- Once a week
- Estimated price
- €13–18
- Schedules at
- Busitalia Umbria
Bus from Assisi to Aeroporto Internazionale dell'Umbria
- Ave. Duration
- 17 min
- Frequency
- 5 times a day
- Estimated price
- €2–3
- Schedules at
- Busitalia Umbria
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus
- Ave. Duration
- 11h 45m
- Frequency
- Twice daily
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 55m
- Frequency
- 5 times a week
- Estimated price
- €85–130
- Website
- Flixbus
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
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Booking & Getting There
Spoleto to Palermo bus services, operated by Busitalia Umbria, arrive at Roma, Autostazione Tiburtina station.
Spoleto to Palermo train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Spoleto to Palermo train tickets online with Omio.
There are 6129+ hotels available in Palermo.






























