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How to get fromSpringfield to Cape Girardeauby bus (Flixbus, Greyhound), car, plane, taxi, train, or bus

Find Transport to Cape Girardeau

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There are 4 ways to get from Springfield to Cape Girardeau by bus (Flixbus, Greyhound), car, plane, taxi, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    4h 49m
    $40–60

  2. Drive  193.9 mi

    cheapest
    1. Drive from Springfield to Cape Girardeaucar car 193.9 mi
    3h 48m
    $36–52

  3. Fly, taxi

    1. Fly from Abraham Lincoln Capital Airport (SPI) to Williamson County Regional Airport (MWA)plane plane SPI - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    5h 25m
    $204–557

  4. Train, bus

    1. Take the train from Springfield to St. Louistrain train Lincoln Service / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    4h 57m
    $78–119

Abraham Lincoln Capital Airport (SPI) to Williamson County Regional Airport (MWA) flights

Calendar5Weekly Planes
Duration4h 5mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Springfield to Cape Girardeau.ExpandLaunch map view
  • Distance: 213.9 mi
  • Duration: 4h 49m

What companies run services between Springfield, IL, USA and Cape Girardeau, MO, USA?

You can take a bus from Springfield SMTD Transfer Center to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 4h 49m.

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