There are 4 ways to get from Springfield to Mayo Clinic by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Rochester
best- Fly from Springfield-Branson National Airport (SGF) to Rochester (RST)plane SGF - RST
6h 59m$91–409Bus
- Take the bus from Springfield to Kansas Citybus
- Take the bus from Kansas City to Albert Leabus
- Take the bus from Albert Lea to Rochesterbus
13h 58mDrive 542.1 mi
- Drive from Springfield to Mayo Cliniccar 542.1 mi
9h 57m$99–143Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Springfield-Branson National Airport (SGF) to Minneapolis–Saint Paul International Airport (MSP)plane SGF - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 42m$163–561
Springfield-Branson National Airport (SGF) to Rochester (RST) flights
Questions & Answers
The cheapest way to get from Springfield to Mayo Clinic is to drive which costs $95 - $150 and takes 9h 57m.
The fastest way to get from Springfield to Mayo Clinic is to fly which takes 6h 59m and costs $90 - $410.
No, there is no direct bus from Springfield to Mayo Clinic. However, there are services departing from Springfield and arriving at Rochester via Kansas City and Albert Lea. The journey, including transfers, takes approximately 13h 58m.
The distance between Springfield and Mayo Clinic is 483 miles. The road distance is 545.3 miles.
The best way to get from Springfield to Mayo Clinic without a car is to bus which takes 13h 58m and costs .
It takes approximately 6h 59m to get from Springfield to Mayo Clinic, including transfers.
Springfield to Mayo Clinic bus services, operated by Jefferson Lines, depart from Springfield station.
The best way to get from Springfield to Mayo Clinic is to fly which takes 6h 59m and costs $90 - $410. Alternatively, you can bus, which costs and takes 13h 58m.
Springfield to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Springfield to Mayo Clinic is 545 miles. It takes approximately 9h 57m to drive from Springfield to Mayo Clinic.
What companies run services between Springfield, MO, USA and Mayo Clinic, MN, USA?
American Airlines, United Airlines, and Delta fly from Springfield-Branson National Airport (SGF) to Rochester (RST) 5 times a day. Alternatively, you can take a bus from Springfield to Mayo Clinic via Kansas City, Albert Lea, and Rochester in around 13h 58m.
- Website
- aa.com
Flights from Springfield-Branson National Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $75–390
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $130–600
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $95–490
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Charlotte
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $170–750
- Website
- united.com
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $95–490
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $140–650
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Houston
- Ave. Duration
- 6h 3m
- When
- Wednesday to Sunday
- Estimated price
- $160–700
- Website
- delta.com
Flights from Springfield-Branson National Airport to Rochester via Atlanta, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 10h 23m
- When
- Every day
- Estimated price
- $130–600
Flights from Springfield-Branson National Airport to Minneapolis–Saint Paul International Airport via Atlanta
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $150–700
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Springfield to Kansas City
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a week
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
Bus from Kansas City to Albert Lea
- Ave. Duration
- 6h 45m
- Frequency
- 3 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
- Website
- example.com
Bus from Albert Lea to Rochester
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
More Questions & Answers
There are 75+ hotels available in Mayo Clinic.