There are 9 ways to get from St. Catharines to Cambridge by bus, plane, bus (Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Toronto Island Airport, fly
best- Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus
- Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)plane YTZ - BOS
5h 51m$126–543Bus (Greyhound)
cheapest- Take the bus from Buffalo to Bostonbus Greyhound US0171
13h 55m$85–176Train
- Take the train from St. Catharines to Buffalotrain VIA Rail
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
14h 47m$162–469Drive 476.4 mi
- Drive from St. Catharines to Cambridgecar 476.4 mi
8h 29m$109–158Train to Rochester, fly
- Take the train from St. Catharines to Rochestertrain
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
6h 33m$122–603Bus to Buffalo Niagara International Airport, fly
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
6h 14m$91–447Bus to Toronto Pearson International Airport, fly
- Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus
- Fly from Toronto Pearson International Airport (YYZ) to Boston Logan Airport (BOS)plane YYZ - BOS
6h 21m$126–613Train to Syracuse Hancock International Airport, fly
- Take the train from St. Catharines to Syracusetrain
- Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane SYR - BOS
8h 37m$123–634Train, bus
- Take the train from St. Catharines to Albanytrain
- Take the bus from Albany Bus Terminal, NY to Worcester Union Stationbus
- Take the train from Worcester to Lansdownetrain
15h 2m$121–340
St. Catharines to Cambridge by bus (Greyhound)
Questions & Answers
The cheapest way to get from St. Catharines to Cambridge is to bus which costs $85 - $180 and takes 13h 55m.
The fastest way to get from St. Catharines to Cambridge is to bus and fly which takes 5h 51m and costs $120 - $550.
No, there is no direct bus from St. Catharines to Cambridge. However, there are services departing from St. Catharines Fairview Mall and arriving at Boston via Niagara Falls and Buffalo. The journey, including transfers, takes approximately 13h 55m.
No, there is no direct train from St. Catharines to Cambridge. However, there are services departing from St. Catharines and arriving at Boston via Buffalo Depew Station. The journey, including transfers, takes approximately 14h 47m.
The distance between St. Catharines and Cambridge is 517 miles. The road distance is 479.1 miles.
The best way to get from St. Catharines to Cambridge without a car is to bus which takes 13h 55m and costs $85 - $180.
It takes approximately 5h 51m to get from St. Catharines to Cambridge, including transfers.
St. Catharines to Cambridge bus services, operated by Greyhound USA, depart from Buffalo station.
St. Catharines to Cambridge train services, operated by VIA Rail, depart from St. Catharines station.
The best way to get from St. Catharines to Cambridge is to bus which takes 13h 55m and costs $85 - $180. Alternatively, you can train, which costs $160 - $470 and takes 14h 47m.
What companies run services between St. Catharines, ON, Canada and Cambridge, MA, USA?
Greyhound USA operates a bus from Buffalo to Boston twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, you can take a train from St. Catharines to Boston via Buffalo Depew Station in around 14h 47m.
- Website
- aa.com
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $65–400
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–420
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–440
Flights from Toronto Pearson International Airport to Boston Logan Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $110–550
Flights from Toronto Pearson International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $55–300
Flights from Toronto Pearson International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $60–320
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $60–400
- Website
- aircanada.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–310
Flights from Toronto Island Airport to Boston Logan Airport via Montreal
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $60–340
Flights from Toronto Pearson International Airport to Boston Logan Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $45–290
Flights from Toronto Pearson International Airport to Boston Logan Airport via Montreal
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $55–310
- Website
- united.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–310
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 41m
- When
- Saturday
- Estimated price
- $75–440
Flights from Toronto Pearson International Airport to Boston Logan Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $45–290
- Website
- flyporter.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $110–480
Flights from Toronto Pearson International Airport to Boston Logan Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $110–550
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–420
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $60–400
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $90–480
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–490
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from St. Catharines to Buffalo
- Ave. Duration
- 2h 28m
- Frequency
- Once daily
- Estimated price
- $12–150
- Website
- VIA Rail
- Escape
- $12–55
- Business
- $40–140
- Business Plus
- $55–150
- Economy
- $13–60
- Economy Plus
- $15–70
Train from St. Catharines to Rochester
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- $28–170
- Website
- VIA Rail
- Escape
- $28–85
- Business
- $60–160
- Business Plus
- $70–170
- Economy
- $30–95
- Economy Plus
- $35–100
Train from St. Catharines to Syracuse
- Ave. Duration
- 4h 42m
- Frequency
- Once daily
- Estimated price
- $50–200
- Website
- VIA Rail
- Escape
- $50–130
- Business
- $85–190
- Business Plus
- $95–200
- Economy
- $55–140
- Economy Plus
- $60–150
Train from St. Catharines to Albany
- Ave. Duration
- 8h 9m
- Frequency
- Once daily
- Estimated price
- $90–250
- Website
- VIA Rail
- Escape
- $90–210
- Business
- $120–240
- Business Plus
- $140–250
- Economy
- $100–220
- Economy Plus
- $110–220
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $150–320
- Website
- Amtrak
Train from Worcester to Lansdowne
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- $7–14
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $7–14
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from St. Catharines, ON - Bus Terminal to Toronto Union Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $14–55
Bus from St. Catharines, ON - Bus Terminal to Toronto Union Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $14–55
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Twice daily
- Estimated price
- $70–140
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $5–9
- Schedules at
- Flixbus USA
Bus from Albany Bus Terminal, NY to Worcester Union Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Albany Bus Terminal, NY to Worcester Union Station
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a week
- Estimated price
- $29–75
- Website
- Peter Pan
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More Questions & Answers
St. Catharines to Cambridge bus services, operated by Greyhound USA, arrive at Boston station.
St. Catharines to Cambridge train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between St. Catharines to Cambridge is 479 miles. It takes approximately 8h 29m to drive from St. Catharines to Cambridge.
Book your St. Catharines to Cambridge train tickets online with Omio.
Book your St. Catharines to Cambridge bus tickets online with Omio.
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