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How to get fromSt. Louis Airport (STL) to Charlestonby plane, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from St. Louis Airport (STL) to Charleston by plane, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS)plane plane STL - CHS
    3h 28m
    $103–529

  2. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    26h 43m
    $150–312

  3. Drive 852.3 mi

    1. Drive from St. Louis Airport (STL) to Charlestoncar car 852.3 mi
    14h 53m
    $156–225

  4. Fly to Hilton Head Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Hilton Head Airport (HHH)plane plane STL - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    6h 15m
    $113–522

  5. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    27h 12m
    $151–308

St. Louis Airport (STL) to Charleston by train and bus

Calendar5Weekly Services
Duration26h 43mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from St. Louis Airport (STL) to Charleston.ExpandLaunch map view
  • Distance: 719.7 mi
  • Duration: 3h 28m

What companies run services between St. Louis Airport (STL), USA and Charleston, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS) every 4 hours. Alternatively, you can take a train from LAMBERT AIRPORT TERMINAL #1 station to Transit Mall via CIVIC CENTER station, St. Louis, Carbondale Intermodal Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 26h 43m.

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