There are 4 ways to get from St. Louis Airport (STL) to Des Moines by plane, bus (Greyhound), rideshare, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
3h 31m$158–779Drive 318 mi
cheapest- Drive from St. Louis Airport (STL) to Des Moinescar 318 mi
6h 21m$58–84Bus (Greyhound)
- Take the bus from St Louis Bus Station to Des Moinesbus Greyhound US0153S
9h 55m$62–124Airport Transfer
- Take the rideshare from St. Louis-STL to Des Moines318 mi
6h 21m
St. Louis Airport (STL) to Des Moines by bus (Greyhound)
Questions & Answers
The cheapest way to get from St. Louis Airport (STL) to Des Moines is to drive which costs $55 - $85 and takes 6h 21m.
The fastest way to get from St. Louis Airport (STL) to Des Moines is to fly which takes 3h 31m and costs $150 - $800.
No, there is no direct bus from St. Louis Airport (STL) to Des Moines. However, there are services departing from Saint Louis and arriving at Des Moines via St Louis Bus Station. The journey, including transfers, takes approximately 9h 55m.
The distance between St. Louis Airport (STL) and Des Moines is 267 miles. The road distance is 319.8 miles.
The best way to get from St. Louis Airport (STL) to Des Moines without a car is to bus which takes 9h 55m and costs $60 - $130.
It takes approximately 3h 31m to get from St. Louis Airport (STL) to Des Moines, including transfers.
St. Louis Airport (STL) to Des Moines bus services, operated by Greyhound USA, depart from St Louis Bus Station.
The best way to get from St. Louis Airport (STL) to Des Moines is to fly which takes 3h 31m and costs $150 - $800. Alternatively, you can bus, which costs $60 - $130 and takes 9h 55m.
St. Louis Airport (STL) to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between St. Louis Airport (STL) to Des Moines is 320 miles. It takes approximately 6h 21m to drive from St. Louis Airport (STL) to Des Moines.
What companies run services between St. Louis Airport (STL), USA and Des Moines, IA, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) hourly. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Des Moines twice daily. Tickets cost $60–120 and the journey takes 8h 30m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $150–850
Flights from Lambert–St. Louis International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 15m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $250–1,200
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $230–1,100
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 30m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- Greyhound
- Website
- https://www.mozio.com
Rideshare from St. Louis-STL to Des Moines
- Ave. Duration
- 6h 21m
- Frequency
- On demand
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More Questions & Answers
Book your St. Louis Airport (STL) to Des Moines bus tickets online with FlixBus.
There are 241+ hotels available in Des Moines.
Check out Blablacar's carpooling service for rideshare options between St. Louis Airport (STL) and Des Moines. A great option if you don't have a driver's licence or want to avoid public transport.