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How to get fromSt. Louis Airport (STL) to La Crosseby plane, train (Amtrak), train, bus, rideshare, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from St. Louis Airport (STL) to La Crosse by plane, train (Amtrak), train, bus, rideshare, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to La Crosse (LSE)plane plane STL - LSE
    4h 5m
    $93–453

  2. Drive 423.9 mi

    cheapest
    1. Drive from St. Louis Airport (STL) to La Crossecar car 423.9 mi
    8h 1m
    $78–112

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    12h 25m
    $172–382

  4. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    14h 24m
    $148–302

  5. Airport Transfer

    1. Take the rideshare from St. Louis-STL to La Crosserideshare rideshare 423.9 mi
    8h 1m

  6. Fly to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (RST)plane plane STL - RST
    2. Take the bus from Rochester to La Crossebus bus
    7h 57m
    $108–524

  7. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    14h 50m
    $110–190

St. Louis Airport (STL) to La Crosse by train (Amtrak)

Calendar21Weekly Trains
Duration12h 25mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from St. Louis Airport (STL) to La Crosse.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 4h 5m

What companies run services between St. Louis Airport (STL), USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Lambert–St. Louis International Airport (STL) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from LAMBERT AIRPORT TERMINAL #1 station to La Crosse Amtrak Station via CIVIC CENTER station, St. Louis, and Chicago Union Station in around 12h 25m.

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