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How to get fromSt. Louis Airport (STL) to San Diegoby plane, bus (Greyhound), train (Amtrak), car, or train

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There are 9 ways to get from St. Louis Airport (STL) to San Diego by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Diego International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)plane plane STL - SAN
    3h 40m
    $130–230

  2. Bus (Greyhound)

    1. Take the bus from Saint Louis to Phoenix Bus Stationbus bus Greyhound US1210
    2. Take the bus from Phoenix Bus Station to San Diego Greyhound Bus Stopbus bus Greyhound US0851S
    38h 41m
    $282–540

  3. Train via Kansas City (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    46h 24m
    $618–1,462

  4. Drive 1,796.2 mi

    1. Drive from St. Louis Airport (STL) to San Diegocar car 1,796.2 mi
    29h 19m
    $328–474

  5. Fly to Los Angeles International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Los Angeles International Airport (LAX)plane plane STL - LAX
    2. Take the train from Los Angeles to San Diegotrain train
    8h 40m
    $172–391

  6. Fly to Mcclellan–Palomar Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcclellan–Palomar Airport (CLD)plane plane STL - CLD
    2. Take the train from Carlsbad Village Station to San Diego - Santa Fe Depottrain train
    9h 53m
    $170–727

  7. Fly to John Wayne Airport Orange County, train

    1. Fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA)plane plane STL - SNA
    2. Take the train from Fullerton Amtrak Station to San Diegotrain train
    11h 29m
    $236–944

  8. Fly to Tijuana International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Tijuana International Airport (TIJ)plane plane STL - TIJ
    9h 53m
    $230–928

  9. Train (Amtrak)

    1. Take the train from St. Louis to Los Angelestrain train Texas Eagle
    2. Take the train from Los Angeles to San Diegotrain train Pacific Surfliner
    2d 16h
    $788–1,688

St. Louis Airport (STL) to San Diego by bus and tram (Greyhound)

Calendar7Weekly Services
Duration38h 41mAverage Duration
Ticket$282Cheapest Price
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Questions & Answers

Map of how to get from St. Louis Airport (STL) to San Diego.ExpandLaunch map view
  • Distance: 1,554.8 mi
  • Duration: 3h 40m

What companies run services between St. Louis Airport (STL), USA and San Diego, CA, USA?

Southwest Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a bus from Saint Louis to America Plaza Station via Phoenix Bus Station, San Diego Greyhound Bus Stop, and Old Town Station in around 38h 41m.

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