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How to get fromSt. Louis Airport (STL) to Winston-Salemby plane, bus (Flixbus, Amtrak, Greyhound), car, bus, bus (Greyhound, Flixbus), or train

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There are 7 ways to get from St. Louis Airport (STL) to Winston-Salem by plane, bus (Flixbus, Amtrak, Greyhound), car, bus, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO)plane plane STL - GSO
    4h 59m
    $171–808

  2. Drive 691.6 mi

    cheapest
    1. Drive from St. Louis Airport (STL) to Winston-Salemcar car 691.6 mi
    12h 37m
    $127–183

  3. Bus via Carbondale

    1. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    19h 46m
    $132–262

  4. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane plane STL - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 3m
    $139–732

  5. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane plane STL - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    5h 55m
    $574–1,015

  6. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    20h 25m
    $132–259

  7. Bus, train

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    21h 31m
    $168–338

St. Louis Airport (STL) to Winston-Salem by train and bus

Calendar10Weekly Services
Duration19h 46mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from St. Louis Airport (STL) to Winston-Salem.ExpandLaunch map view
  • Distance: 623.3 mi
  • Duration: 4h 59m

What companies run services between St. Louis Airport (STL), USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a train from LAMBERT AIRPORT TERMINAL #1 station to Winston Salem(Trans Center) via CIVIC CENTER station, St Louis Bus Station, Carbondale Intermodal Station, and Atlanta Bus Station in around 19h 46m.

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