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How to get fromSt. Louis to Ankenyby bus (Greyhound), train, bus, car, plane, or bus (Flixbus, Amtrak, Greyhound)

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There are 7 ways to get from St. Louis to Ankeny by bus (Greyhound), train, bus, car, plane, or bus (Flixbus, Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Kansas City (Greyhound)

    best
    1. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus Greyhound US0156
    8h 22m
    $81–144

  2. Drive  339.3 mi

    cheapest
    1. Drive from St. Louis to Ankenycar car 339.3 mi
    6h 43m
    $62–90

  3. Train, bus via Kansas City

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus Greyhound US0156
    10h 49m
    $121–242

  4. Fly to Des Moines

    1. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    6h 11m
    $162–942

  5. Train, bus

    1. Take the train from St. Louis to Bloomington-Normaltrain train Lincoln Service / ...
    2. Take the bus from Bloomington-Normal to Des Moinesbus bus Greyhound US0157S
    10h 20m
    $101–195

  6. Bus

    1. Take the bus from St Louis Bus Station to Springfield SMTD Transfer Centerbus bus
    2. Take the bus from Springfield to Galesburg Amtrak Stationbus bus
    3. Take the bus from Galesburg to Des Moinesbus bus
    11h 43m
    $99–157

  7. Fly to Fort Dodge Municipal Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Dodge Municipal Airport (FOD)plane plane STL - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Ankenycar car
    7h 24m
    $92–466

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

Calendar129Weekly Planes
Duration4h 55mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Ankeny.ExpandLaunch map view
  • Distance: 449 mi
  • Duration: 8h 22m

What companies run services between St. Louis, MO, USA and Ankeny, IA, USA?

You can take a bus from St Louis Bus Station to Ankeny via Kansas City Bus Station and Des Moines in around 8h 22m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) hourly.

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Train operators
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