There are 3 ways to get from St. Louis to Anna by bus (Flixbus, Amtrak), car, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus FlixBus N2521
2h 15m$60–78Drive 115.8 mi
cheapest- Drive from St. Louis to Annacar 115.8 mi
2h 40m$22–31Bus, taxi
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
- Take the taxi from Cape Girardeau to Annataxi
2h 42m$81–106
Comparing Your Travel Options
The cheapest way to get from St. Louis to Anna is to drive which costs $21 - $35 and takes 2h 40m.
The fastest way to get from St. Louis to Anna is to bus which takes 2h 15m and costs $60 - $80.
No, there is no direct bus from St. Louis station to Anna station. However, there are services departing from St Louis Bus Station and arriving at Carbondale Intermodal Station via . The journey, including transfers, takes approximately 2h 15m.
The distance between St. Louis and Anna is 117 miles. The road distance is 116.5 miles.
The best way to get from St. Louis to Anna without a car is to bus which takes 2h 15m and costs $60 - $80.
It takes approximately 2h 15m to get from St. Louis to Anna, including transfers.
St. Louis to Anna bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Anna bus services, operated by Flixbus USA, arrive at Carbondale Intermodal Station.
Yes, the driving distance between St. Louis to Anna is 117 miles. It takes approximately 2h 40m to drive from St. Louis to Anna.
There are 18+ hotels available in Anna.
What companies run services between St. Louis, MO, USA and Anna, IL, USA?
Flixbus USA operates a bus from St Louis Bus Station to Carbondale Intermodal Station 5 times a week. Tickets cost $15–23 and the journey takes 1h 50m. Amtrak also services this route once daily.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
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