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How to get fromSt. Louis to Antiochby train (Amtrak), bus, train, car, or plane

Find Transport to Antioch

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There are 9 ways to get from St. Louis to Antioch by train (Amtrak), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Antiochtrain train Ncs
    7h 35m
    $97–193

  2. Bus, train

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    2. Take the train from Chicago Union Station to Antiochtrain train Ncs
    8h 54m
    $57–93

  3. Drive 321.2 mi

    1. Drive from St. Louis to Antiochcar car 321.2 mi
    6h
    $59–85

  4. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from O'Hare Transfer to Antiochtrain train
    5h 34m
    $278–764

  5. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Chicago Union Station to Antiochtrain train
    6h 8m
    $66–386

  6. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    6h 43m
    $80–371

  7. Fly Lambert–St. Louis International Airport to General Mitchell International Airport, bus, train

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Take the train from O'Hare Transfer to Antiochtrain train
    7h 35m
    $524–954

  8. Bus to Williamson County Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    7h 34m
    $132–368

  9. Bus to Decatur Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus bus
    2. Fly from Decatur Airport (DEC) to Chicago O'Hare International Airport (ORD)plane plane DEC - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    7h 39m
    $72–345

St. Louis to Antioch by train

Calendar35Weekly Trains
Duration7h 35mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Antioch.ExpandLaunch map view
  • Distance: 333.5 mi
  • Duration: 7h 35m

What companies run services between St. Louis, MO, USA and Antioch, IL, USA?

You can take a train from St. Louis to Antioch via Chicago Union Station in around 7h 35m.

Airlines
Train operators
Bus operators

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