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How to get fromSt. Louis to Apexby plane, bus, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 4 ways to get from St. Louis to Apex by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, line 311 bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane plane STL - RDU
    2. Take the bus from Regional Transit Center to E Williams St at S Hughes Stbus bus
    5h 43m
    $558–1,108
  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Durhambus bus FlixBus N2471 / ...
    22h 21m
    $132–265
  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Carytrain train Floridian
    31h 38m
    $357–817
  4. Drive 767.7 mi

    1. Drive from St. Louis to Apexcar car 767.7 mi
    14h 2m
    $141–203

St. Louis to Apex by bus

Calendar12Weekly Buses
Duration22h 21mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Apex, NC, USA?

You can take a bus from St Louis Bus Station to E Williams St at S Hughes St via Atlanta Bus Station, Durham, Durham Station, and Regional Transit Center in around 22h 21m. Alternatively, you can take a train from St. Louis to N Salem St at Hunter Street OB via Chicago Union Station, Cary, and Cary Depot in around 31h 38m.

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