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How to get fromSt. Louis to Ashlandby bus, train, bus (Greyhound), car, plane, or train (Amtrak)

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There are 7 ways to get from St. Louis to Ashland by bus, train, bus (Greyhound), car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train Cardinal
    11h 55m
    $122–249

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus to Ashland Bus Stationbus bus Greyhound US0140
    12h 50m
    $75–171

  3. Drive 448 mi

    1. Drive from St. Louis to Ashlandcar car 448 mi
    7h 27m
    $82–119

  4. Fly to Tri-State Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Tri-State Airport (HTS)plane plane STL - HTS
    7h 10m
    $126–582

  5. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Ashland Amtrak Stationtrain train Cardinal
    17h 45m
    $230–495

  6. Fly to Yeager Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Yeager Airport (CRW)plane plane STL - CRW
    2. Take the train from Charleston Station to Ashland Amtrak Stationtrain train
    8h 38m
    $148–664

  7. Fly to John Glenn Columbus International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from Columbus to Ashland Bus Stationbus bus
    7h 16m
    $814–982

St. Louis to Ashland by bus and train

Calendar3Weekly Services
Duration11h 55mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Ashland.ExpandLaunch map view
  • Distance: 512.7 mi
  • Duration: 11h 55m

What companies run services between St. Louis, MO, USA and Ashland, KY, USA?

You can take a bus from St Louis Bus Station to Ashland Bus Station via Columbus in around 12h 50m. Alternatively, American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Tri-State Airport (HTS) twice daily.

Airlines
Train operators
Bus operators

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