Rome2Rio

How to get fromSt. Louis to Biloxiby plane, bus, train, or car

Find Transport to Biloxi

See all options

There are 7 ways to get from St. Louis to Biloxi by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT)plane plane STL - GPT
    5h 47m
    $138–648

  2. Fly to Pensacola International Airport, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    7h 31m
    $74–342

  3. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus Greyhound US1173
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train Amtrak Mardi Gras Service / ...
    19h 13m
    $135–231

  4. Bus, train via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    19h 16m
    $205–527

  5. Drive  651.3 mi

    1. Drive from St. Louis to Biloxicar car 651.3 mi
    10h 51m
    $119–172

  6. Fly to Mobile Regional Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Mobile Regional Airport (MOB)plane plane STL - MOB
    2. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    7h 42m
    $120–516

  7. Fly to Louis Armstrong New Orleans International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    6h 59m
    $426–912

St. Louis to Biloxi by bus and train

Calendar7Weekly Services
Duration19h 13mAverage Duration
Ticket$135Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from St. Louis to Biloxi.ExpandLaunch map view
  • Distance: 607.7 mi
  • Duration: 5h 47m

What companies run services between St. Louis, MO, USA and Biloxi, MS, USA?

American Airlines, United Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound