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How to get fromSt. Louis to Biloxiby plane, bus, train, bus (Greyhound, Flixbus), or car

Find Transport to Biloxi

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There are 6 ways to get from St. Louis to Biloxi by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT)plane plane STL - GPT
    6h 35m
    $128–528

  2. Drive  651.3 mi

    cheapest
    1. Drive from St. Louis to Biloxicar car 651.3 mi
    10h 51m
    $119–172

  3. Bus, train

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    19h 16m
    $395–642

  4. Bus

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus Greyhound US1173
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus Greyhound US0602
    19h 20m
    $140–210

  5. Fly to Louis Armstrong New Orleans International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    6h 59m
    $516–928

  6. Fly to Mobile Regional Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Mobile Regional Airport (MOB)plane plane STL - MOB
    2. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    7h 42m
    $120–518

St. Louis to Biloxi by bus and train

Calendar7Weekly Services
Duration19h 16mAverage Duration
Ticket$395Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Biloxi.ExpandLaunch map view
  • Distance: 607.7 mi
  • Duration: 6h 35m

What companies run services between St. Louis, MO, USA and Biloxi, MS, USA?

United Airlines, American Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Biloxi Transit Center via New Orleans Bus Station in around 19h 20m.

Airlines
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