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How to get fromSt. Louis to Biltmore Estateby plane, car, bus (Greyhound, Flixbus), or shuttle

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There are 6 ways to get from St. Louis to Biltmore Estate by plane, car, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, drive

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Biltmore Estatecar car
    6h 16m
    $134–720

  2. Fly to Asheville Regional Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    8h 25m
    $94–494

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Asheville, NCbus bus
    21h 38m
    $159–298

  4. Drive 593.3 mi

    1. Drive from St. Louis to Biltmore Estatecar car 593.3 mi
    10h 24m
    $109–157

  5. Fly to Mcghee Tyson Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Biltmore Estatecar car
    8h 22m
    $154–838

  6. Fly to Tri-Cities Regional Tn/Va Airport, shuttle

    1. Fly from Lambert–St. Louis International Airport (STL) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane STL - TRI
    2. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    10h 4m
    $398–944

Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) flights

Calendar126Weekly Planes
Duration4h 44mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Biltmore Estate.ExpandLaunch map view
  • Distance: 601.9 mi
  • Duration: 6h 16m

What companies run services between St. Louis, MO, USA and Biltmore Estate, NC, USA?

You can take a bus from St Louis Bus Station to Biltmore Estate via Atlanta Bus Station, Charlotte Bus Station, Asheville, NC, ART Station, and Hendersonville Rd at W Chapel Rd in around 21h 38m. Alternatively, Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL) hourly.

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