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How to get fromSt. Louis to Bristolby plane, bus, train, car, shuttle, taxi, bus (Greyhound, Flixbus), or bus (Flixbus, Amtrak, Greyhound)

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There are 8 ways to get from St. Louis to Bristol by plane, bus, train, car, shuttle, taxi, bus (Greyhound, Flixbus), or bus (Flixbus, Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-Cities Regional Tn/Va Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane STL - TRI
    5h 27m
    $168–712

  2. Drive 545.4 mi

    cheapest
    1. Drive from St. Louis to Bristolcar car 545.4 mi
    10h 28m
    $100–144

  3. Bus, train

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Wythevillebus bus
    4. Take the bus from Wytheville Rural King Parking Lot to Bristol Exit 5 Park & Ride Lotbus bus
    19h 52m
    $181–357

  4. Fly to Mcghee Tyson Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Bristolcar car
    7h 36m
    $144–788

  5. Fly to Asheville Regional Airport, shuttle, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    2. Take a shuttle bus from Asheville Airport to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristoltaxi taxi
    9h 4m
    $350–760

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Bristolcar car
    7h 47m
    $148–742

  7. Bus

    1. Take the bus from St Louis Bus Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    3. Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus bus Swb
    4. Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus bus
    21h 20m
    $139–254

  8. Bus via Carbondale

    1. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    4. Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus bus Swb
    5. Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus bus
    21h 30m
    $136–264

St. Louis to Bristol by bus

Calendar7Weekly Buses
Duration21h 20mAverage Duration
Ticket$139Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Bristol.ExpandLaunch map view
  • Distance: 492.1 mi
  • Duration: 5h 27m

What companies run services between St. Louis, MO, USA and Bristol, VA, USA?

Delta and American Airlines fly from Lambert–St. Louis International Airport (STL) to Tri-Cities Regional Tn/Va Airport (TRI) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Bristol Exit 5 Park & Ride Lot via Nashville Bus Station, 3rd St Station Slip D, Exit 118 - Park and Ride, and Christiansburg in around 21h 20m.

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