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How to get fromSt. Louis to Bryanby train (Amtrak), bus (Flixbus, Amtrak), car, plane, train, bus (Greyhound, Amtrak), or bus

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There are 11 ways to get from St. Louis to Bryan by train (Amtrak), bus (Flixbus, Amtrak), car, plane, train, bus (Greyhound, Amtrak), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    9h 8m
    $146–305

  2. Drive 406.8 mi

    cheapest
    1. Drive from St. Louis to Bryancar car 406.8 mi
    7h 13m
    $75–108

  3. Bus via Chicago

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    10h 27m
    $111–175

  4. Fly to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    7h 49m
    $118–500

  5. Bus

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Bryan Amtrak Stationbus bus
    11h 35m
    $87–164

  6. Fly to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    8h 6m
    $330–828

  7. Fly to Detroit, bus, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    8h 10m
    $494–1,024

  8. Fly to Cleveland-Hopkins International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    8h 20m
    $546–1,016

  9. Fly to Fort Wayne International Airport, bus, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Wayne International Airport (FWA)plane plane STL - FWA
    2. Take the bus from Fort Wayne, IN to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 39m
    $128–516

  10. Fly to John Glenn Columbus International Airport, bus, train

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Toledo Bus Stopbus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 46m
    $840–1,012

  11. Fly to General Mitchell International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    9h 59m
    $566–1,046

St. Louis to Bryan by train (Amtrak)

Calendar14Weekly Trains
Duration9h 8mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Bryan.ExpandLaunch map view
  • Distance: 459.9 mi
  • Duration: 9h 8m

What companies run services between St. Louis, MO, USA and Bryan, OH, USA?

You can take a train from St. Louis to Bryan Amtrak Station via Chicago Union Station in around 9h 8m. Alternatively, you can take a bus from St Louis Bus Station to Bryan Amtrak Station via Chicago Bus Station and Chicago Union Station in around 10h 27m.

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