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How to get fromSt. Louis to Cairoby plane, taxi, bus (Greyhound, Flixbus), or car

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There are 6 ways to get from St. Louis to Cairo by plane, taxi, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tallahassee, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Tallahassee (TLH)plane plane STL - TLH
    2. Take the taxi from Tallahassee (TLH) to Cairotaxi taxi
    6h 3m
    $252–812

  2. Fly to Southwest Georgia Regional Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Southwest Georgia Regional Airport (ABY)plane plane STL - ABY
    2. Drive from Southwest Georgia Regional Airport (ABY) to Cairocar car
    6h 52m
    $102–498

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus FlixBus N2521
    2. Take the bus from Atlanta Bus Station to Thomasville Travel Centerbus bus Greyhound US0636 / ...
    17h 1m
    $167–293

  4. Drive 753.4 mi

    1. Drive from St. Louis to Cairocar car 753.4 mi
    13h 23m
    $138–199

  5. Fly to Valdosta, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Valdosta (VLD)plane plane STL - VLD
    2. Drive from Valdosta (VLD) to Cairocar car
    7h 28m
    $108–518

  6. Fly to Northwest Florida Beaches International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Cairocar car
    6h
    $114–518

Lambert–St. Louis International Airport (STL) to Tallahassee (TLH) flights

Calendar67Weekly Planes
Duration5h 12mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Cairo.ExpandLaunch map view
  • Distance: 723.8 mi
  • Duration: 6h 3m

What companies run services between St. Louis, MO, USA and Cairo, GA, USA?

You can take a bus from St Louis Bus Station to Cairo via Atlanta Bus Station and Thomasville Travel Center in around 17h 1m.

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