There are 2 ways to get from St. Louis to Cape Girardeau by bus (Greyhound) or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Comparing Your Travel Options
The cheapest way to get from St. Louis to Cape Girardeau is to drive which costs $21 - $35 and takes 1h 58m.
The fastest way to get from St. Louis to Cape Girardeau is to drive which takes 1h 58m and costs $21 - $35.
No, there is no direct bus from St. Louis station to Cape Girardeau. However, there are services departing from St Louis Bus Station and arriving at Cape Girardeau via . The journey, including transfers, takes approximately 2h 9m.
The distance between St. Louis and Cape Girardeau is 116 miles. The road distance is 116 miles.
The best way to get from St. Louis to Cape Girardeau without a car is to bus which takes 2h 9m and costs $27 - $40.
It takes approximately 2h 9m to get from St. Louis to Cape Girardeau, including transfers.
St. Louis to Cape Girardeau bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Cape Girardeau bus services, operated by Greyhound USA, arrive at Cape Girardeau station.
Yes, the driving distance between St. Louis to Cape Girardeau is 116 miles. It takes approximately 1h 58m to drive from St. Louis to Cape Girardeau.
Book your St. Louis to Cape Girardeau bus tickets online with Omio.
What companies run services between St. Louis, MO, USA and Cape Girardeau, MO, USA?
Greyhound USA operates a bus from St Louis Bus Station to Cape Girardeau once daily. Tickets cost $20–35 and the journey takes 2h 5m.
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
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Booking & Getting There
There are 23+ hotels available in Cape Girardeau.


