Rome2Rio

How to get fromSt. Louis to Charlotteby plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Find Transport to Charlotte

See all options

There are 6 ways to get from St. Louis to Charlotte by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane plane STL - CLT
    4h 4m
    $126–706

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    16h 40m
    $117–225

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    34h 6m
    $443–988

  4. Drive 709.3 mi

    1. Drive from St. Louis to Charlottecar car 709.3 mi
    12h 4m
    $130–187

  5. Bus via Atlanta

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus FlixBus N2470
    16h 59m
    $120–218

  6. Bus via Sandy Springs

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta to Charlottebus bus Charlotte
    19h 55m
    $136–236

St. Louis to Charlotte by bus

Calendar12Weekly Buses
Duration16h 40mAverage Duration
Ticket$117Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Charlotte.ExpandLaunch map view
  • Distance: 595.2 mi
  • Duration: 4h 4m

What companies run services between St. Louis, MO, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Charlotte Bus Station via Atlanta Bus Station in around 16h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers