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How to get fromSt. Louis to Charlotteby plane, bus (Amtrak, Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from St. Louis to Charlotte by plane, bus (Amtrak, Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane plane STL - CLT
    4h 4m
    $126–706

  2. Bus via Carbondale

    cheapest
    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    16h 24m
    $118–236

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    34h 6m
    $498–1,003

  4. Drive 709.3 mi

    1. Drive from St. Louis to Charlottecar car 709.3 mi
    12h 4m
    $130–187

  5. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    16h 40m
    $122–232

St. Louis to Charlotte by bus and subway

Calendar5Weekly Services
Duration16h 24mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Charlotte.ExpandLaunch map view
  • Distance: 595.2 mi
  • Duration: 4h 4m

What companies run services between St. Louis, MO, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT) every 4 hours. Alternatively, you can take a bus from St. Louis to Charlotte Bus Station via Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 16h 24m.

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