There are 6 ways to get from St. Louis to Chicago Union Station by train (Amtrak), bus (Flixbus), car, plane, subway, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
4h 55m$90–190Bus
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
6h 14m$50–85Drive 292.2 mi
- Drive from St. Louis to Chicago Union Stationcar 292.2 mi
5h 3m$54–77Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, subway
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the subway from Midway to Quincysubway
3h 27m$60–368Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
3h 53m$274–708Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport
- Take the train from St. Louis to Springfieldtrain
- Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane SPI - ORD
5h 3m$76–304
St. Louis to Chicago Union Station by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Chicago Union Station is to bus which costs $50 - $85 and takes 6h 14m.
The fastest way to get from St. Louis to Chicago Union Station is to fly and subway which takes 3h 27m and costs $55 - $370.
Yes, there is a direct bus departing from St Louis Bus Station station and arriving at Chicago Bus Station station. Services depart three times a day, and operate every day. The journey takes approximately 6h 5m.
Yes, there is a direct train departing from St. Louis and arriving at Chicago Union Station station. Services depart five times a day, and operate every day. The journey takes approximately 4h 55m.
The distance between St. Louis and Chicago Union Station is 282 miles. The road distance is 293.9 miles.
The best way to get from St. Louis to Chicago Union Station without a car is to train which takes 4h 55m and costs $90 - $190.
The train from St. Louis to Chicago Union Station takes 4h 55m including transfers and departs five times a day.
St. Louis to Chicago Union Station bus services, operated by FlixBus-us, depart from St Louis Bus Station.
St. Louis to Chicago Union Station train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Chicago Union Station is to train which takes 4h 55m and costs $90 - $190. Alternatively, you can bus, which costs $50 - $85 and takes 6h 14m, you could also fly, which costs $270 - $750 and takes 3h 53m.
What companies run services between St. Louis, MO, USA and Chicago Union Station, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m. Alternatively, FlixBus-us operates a bus from St Louis Bus Station to Chicago Bus Station 3 times a day, and the journey takes 6h 5m. Flixbus USA also services this route twice daily.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–360
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
Flights from Abraham Lincoln Capital Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $30–220
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Midway to Quincy
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
- Website
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
St. Louis to Chicago Union Station bus services, operated by FlixBus-us, arrive at Chicago Bus Station.
St. Louis to Chicago Union Station train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Chicago Union Station is 294 miles. It takes approximately 5h 3m to drive from St. Louis to Chicago Union Station.
Book your St. Louis to Chicago Union Station train tickets online with Omio.
Book your St. Louis to Chicago Union Station bus tickets online with Omio and FlixBus.
There are 1199+ hotels available in Chicago Union Station.