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How to get fromSt. Louis to Chillicotheby plane, bus, bus (Greyhound), or car

Find Transport to Chillicothe

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There are 4 ways to get from St. Louis to Chillicothe by plane, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Glenn Columbus International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from Columbus - Mound St to Chillicothebus bus
    6h 13m
    $814–976

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus - Mound St to Chillicothebus bus Columbus
    11h 47m
    $74–165

  3. Drive 428.4 mi

    1. Drive from St. Louis to Chillicothecar car 428.4 mi
    7h 24m
    $79–113

  4. Fly to Cleveland-Hopkins International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    2. Take the bus from Cleveland Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Chillicothebus bus
    8h 58m
    $526–990

Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH) flights

Calendar18Weekly Planes
Duration2h 24mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Chillicothe.ExpandLaunch map view
  • Distance: 475.9 mi
  • Duration: 6h 13m

What companies run services between St. Louis, MO, USA and Chillicothe, OH, USA?

You can take a bus from St Louis Bus Station to Chillicothe via Columbus - Mound St and Chillicothe in around 11h 47m.

Airlines
Bus operators

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