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How to get fromSt. Louis to Cincinnatiby bus (Greyhound, Flixbus), car, plane, bus (Greyhound), or bus

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There are 7 ways to get from St. Louis to Cincinnati by bus (Greyhound, Flixbus), car, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Dayton Trotwood Bus Stationbus bus Greyhound US0421
    2. Take the bus from Dayton Trotwood Bus Station to Cincinnatibus bus FlixBus N2642
    8h 50m
    $62–114

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus Detroit / ...
    9h 35m
    $52–150

  3. Drive 345.4 mi

    1. Drive from St. Louis to Cincinnaticar car 345.4 mi
    5h 48m
    $63–92

  4. Fly Lambert–St. Louis International Airport to Covington

    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    5h 35m
    $114–704

  5. Bus via Evansville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    9h 20m
    $70–148

  6. Fly Midamerica St. Louis Airport to Covington

    1. Fly from Midamerica St. Louis Airport (BLV) to Covington (CVG)plane plane BLV - CVG
    7h 19m
    $188–782

  7. Fly Lambert–St. Louis International Airport to John Glenn Columbus International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from Columbus to Cincinnatibus bus
    7h 28m
    $124–690

St. Louis to Cincinnati by bus

Calendar4Weekly Buses
Duration8h 50mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Cincinnati.ExpandLaunch map view
  • Distance: 403.6 mi
  • Duration: 8h 50m

What companies run services between St. Louis, MO, USA and Cincinnati, OH, USA?

You can take a bus from St Louis Bus Station to Cincinnati via Dayton Trotwood Bus Station in around 8h 50m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Covington (CVG) hourly.

Airlines
Bus operators

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