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How to get fromSt. Louis to Clarksdaleby bus, train, taxi, car, or plane

Find Transport to Clarksdale

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There are 5 ways to get from St. Louis to Clarksdale by bus, train, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the train from Carbondale to Marks Stationtrain train City of New Orleans
    9h 55m
    $138–285

  2. Drive 356.4 mi

    cheapest
    1. Drive from St. Louis to Clarksdalecar car 356.4 mi
    5h 57m
    $65–94

  3. Bus, taxi (Greyhound)

    1. Take the bus from St Louis Bus Station to Batesville(Terza One Stop Shop)bus bus Greyhound US1173
    2. Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi taxi
    9h 55m
    $170–243

  4. Fly to Bill And Hillary Clinton National Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Bill And Hillary Clinton National Airport (LIT)plane plane STL - LIT
    2. Drive from Bill And Hillary Clinton National Airport (LIT) to Clarksdalecar car
    8h 5m
    $228–1,142

  5. Fly to Memphis, bus, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    2. Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus bus
    3. Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi taxi
    9h
    $252–920

Lambert–St. Louis International Airport (STL) to Bill And Hillary Clinton National Airport (LIT) flights

Calendar123Weekly Planes
Duration4h 50mAverage Duration
Ticket$201Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Clarksdale.ExpandLaunch map view
  • Distance: 399.6 mi
  • Duration: 9h 55m

What companies run services between St. Louis, MO, USA and Clarksdale, MS, USA?

There is no direct connection from St. Louis to Clarksdale. However, you can take the bus to Carbondale, walk to Carbondale, take the train to Marks Station, then take the taxi to Clarksdale. Alternatively, you can take the bus to Batesville(Terza One Stop Shop) then take the taxi to Clarksdale.

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