Rome2Rio

How to get fromSt. Louis to Clarksvilleby bus (Greyhound), car, or plane

Find Transport to Clarksville

See all options

There are 4 ways to get from St. Louis to Clarksville by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus Greyhound US0185 / ...
    2. Take the bus from Evansville, IN to Louisville, KYbus bus Evansville
    8h 2m
    $61–105

  2. Drive 258.8 mi

    cheapest
    1. Drive from St. Louis to Clarksvillecar car 258.8 mi
    4h 19m
    $48–69

  3. Fly to Louisville International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    7h 15m
    $104–658

  4. Fly to Blue Grass Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    2. Drive from Lexington-Airport-LEX to Clarksvillecar car
    6h 52m
    $186–1,022

St. Louis to Clarksville by bus and foot

Calendar7Weekly Services
Duration8h 2mAverage Duration
Ticket$61Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Clarksville.ExpandLaunch map view
  • Distance: 290 mi
  • Duration: 8h 2m

What companies run services between St. Louis, MO, USA and Clarksville, Clark County, IN, USA?

You can take a bus from St Louis Bus Station to Eastern @ Kopp via Evansville, IN, Louisville, KY, and Liberty @ Roy Wilkins in around 8h 2m. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) hourly.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers