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How to get fromSt. Louis to Columbusby plane, bus, or car

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There are 4 ways to get from St. Louis to Columbus by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR)plane plane STL - GTR
    5h 31m
    $122–508

  2. Drive  431.2 mi

    cheapest
    1. Drive from St. Louis to Columbuscar car 431.2 mi
    7h 36m
    $74–107

  3. Bus, drive

    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    3. Drive from Tupelo to Columbuscar car
    9h 22m
    $75–121

  4. Fly to Birmingham–Shuttlesworth International Airport, bus, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane plane STL - BHM
    2. Take the bus from Birmingham-Shuttlesworth to Embassy Suites by Hilton Tuscaloosa Alabama Dowtownbus bus
    3. Drive from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Columbuscar car
    8h 17m
    $122–482

Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR) flights

Calendar33Weekly Planes
Duration4h 19mAverage Duration
Ticket$85Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Columbus.ExpandLaunch map view
  • Distance: 404.7 mi
  • Duration: 5h 31m

What companies run services between St. Louis, MO, USA and Columbus, MS, USA?

Delta, American Airlines, and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR) 5 times a day.

Airlines
Bus operators

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