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How to get fromSt. Louis to Columbusby bus, car, or plane

Find Transport to Columbus

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There are 4 ways to get from St. Louis to Columbus by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    3. Drive from Tupelo to Columbuscar car
    8h 37m
    $73–134

  2. Drive 431.2 mi

    1. Drive from St. Louis to Columbuscar car 431.2 mi
    7h 36m
    $79–114

  3. Fly to Golden Triangle Regional Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR)plane plane STL - GTR
    6h 5m
    $138–548

  4. Fly to Birmingham–Shuttlesworth International Airport, bus, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane plane STL - BHM
    2. Take the bus from Birmingham-Shuttlesworth to Embassy Suites by Hilton Tuscaloosa Alabama Dowtownbus bus
    3. Drive from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Columbuscar car
    8h 23m
    $178–834

Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR) flights

Calendar34Weekly Planes
Duration4h 44mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Columbus.ExpandLaunch map view
  • Distance: 452.5 mi
  • Duration: 8h 37m

What companies run services between St. Louis, MO, USA and Columbus, MS, USA?

Delta, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR) 5 times a day.

Airlines
Bus operators

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