There are 5 ways to get from St. Louis to DeSoto by plane, tram, bus, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Dallas, tram, line 306 bus
best- Fly from Lambert–St. Louis International Airport (STL) to Dallas (DAL)plane STL - DAL
- Take the tram from Inwood/Love Field Station to West End Stationtram
- Take the bus from Griffin @ Main - S - Ns to Glenn Heights P & Rbus
4h 53m$92–472Bus
- Take the bus from St Louis Bus Station to Oklahoma City Bus Stationbus Greyhound US1210
- Take the bus from Oklahoma City Bus Station to Downtown Dallas / Deep Ellumbus FlixBus 2242
16h 2m$116–210Train (Amtrak)
- Take the train from St. Louis to Dallastrain Texas Eagle
17h 10m$236–466Drive 643.1 mi
- Drive from St. Louis to DeSotocar 643.1 mi
10h 46m$118–170Fly to Dallas/Fort Worth International Airport, line 306 bus
- Fly from Lambert–St. Louis International Airport (STL) to Dallas/Fort Worth International Airport (DFW)plane STL - DFW
- Take the bus from Griffin @ Main - S - Ns to Glenn Heights P & Rbus
6h 6m$348–608
St. Louis to DeSoto by bus
Questions & Answers
The cheapest way to get from St. Louis to DeSoto is to bus which costs $110 - $210 and takes 16h 2m.
The fastest way to get from St. Louis to DeSoto is to fly and tram and line 306 bus which takes 4h 53m and costs $90 - $480.
No, there is no direct bus from St. Louis station to DeSoto. However, there are services departing from St Louis Bus Station and arriving at Glenn Heights P & R via Oklahoma City Bus Station, Gaston @ Good Latimer - S- Ns and Wood @ Record - W - Fs. The journey, including transfers, takes approximately 16h 2m.
No, there is no direct train from St. Louis to DeSoto. However, there are services departing from St. Louis and arriving at Dallas via . The journey, including transfers, takes approximately 17h 10m.
The distance between St. Louis and DeSoto is 586 miles. The road distance is 646.9 miles.
The best way to get from St. Louis to DeSoto without a car is to bus which takes 16h 2m and costs $110 - $210.
It takes approximately 4h 53m to get from St. Louis to DeSoto, including transfers.
St. Louis to DeSoto bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to DeSoto train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to DeSoto is to bus which takes 16h 2m and costs $110 - $210. Alternatively, you can train, which costs $230 - $470 and takes 17h 10m.
What companies run services between St. Louis, MO, USA and DeSoto, TX, USA?
You can take a bus from St Louis Bus Station to Glenn Heights P & R via Oklahoma City Bus Station, Downtown Dallas / Deep Ellum, Gaston @ Good Latimer - S- Ns, Houston @ Young - S - Mb, and Wood @ Record - W - Fs in around 16h 2m. Alternatively, Amtrak operates a train from St. Louis to Dallas once daily. Tickets cost $230–470 and the journey takes 15h 58m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Dallas
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $80–460
Flights from Lambert–St. Louis International Airport to Dallas via Kansas City
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Dallas via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–550
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Dallas/Fort Worth International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $90–550
- Website
- flyfrontier.com
Flights from Lambert–St. Louis International Airport to Dallas/Fort Worth International Airport
- Ave. Duration
- 2h 2m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $160–600
- Phone
- +1 214-979-1111
- Website
- dart.org
Tram from Inwood/Love Field Station to West End Station
- Ave. Duration
- 11 min
- Frequency
- Every 15 minutes
- Estimated price
- $3
- Website
- https://www.dart.org
- Adult - 3 Hour Pass - Unlimited Rides
- $3
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Dallas
- Ave. Duration
- 15h 58m
- Frequency
- Once daily
- Estimated price
- $230–470
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 214-979-1111
- Website
- dart.org
Bus from Griffin @ Main - S - Ns to Glenn Heights P & R
- Ave. Duration
- 28 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://www.dart.org
- Adult - 3 Hour Pass - Unlimited Rides
- $3
Bus from Griffin @ Main - S - Ns to Glenn Heights P & R
- Ave. Duration
- 28 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://www.dart.org
- Adult - 3 Hour Pass - Unlimited Rides
- $3
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Oklahoma City Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- $80–150
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Oklahoma City Bus Station to Downtown Dallas / Deep Ellum
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $30–55
- Schedules at
- flixbus.com
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More Questions & Answers
St. Louis to DeSoto bus services, operated by Greyhound USA, arrive at Oklahoma City Bus Station.
St. Louis to DeSoto train services, operated by Amtrak, arrive at Dallas station.
Yes, the driving distance between St. Louis to DeSoto is 647 miles. It takes approximately 10h 46m to drive from St. Louis to DeSoto.
There are 1031+ hotels available in DeSoto.










