There are 6 ways to get from St. Louis to Duncan by plane, bus (Greyhound, Flixbus), car, or bus (Amtrak, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane STL - GSP
4h 55m$140–686Fly to Asheville Regional Airport, drive
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane STL - AVL
- Drive from Asheville-Airport-AVL to Duncancar
6h 3m$92–466Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus Greyhound US0186
- Take the bus from Atlanta Bus Station to Greenvillebus Greyhound US0670
15h 18m$146–228Drive 652 mi
- Drive from St. Louis to Duncancar 652 mi
11h 6m$119–172Fly to Columbia, drive
- Fly from Lambert–St. Louis International Airport (STL) to Columbia (CAE)plane STL - CAE
- Drive from Columbia-Airport-CAE to Duncancar
6h 45m$100–480Bus via Carbondale
- Take the bus from St. Louis to Carbondalebus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Servicios Zapata - Spartanburgbus
17h 11m$138–230
Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Duncan is to drive which costs $110 - $180 and takes 11h 6m.
The fastest way to get from St. Louis to Duncan is to fly which takes 4h 55m and costs $140 - $700.
No, there is no direct bus from St. Louis station to Duncan. However, there are services departing from St Louis Bus Station and arriving at Greenville via Atlanta Bus Station. The journey, including transfers, takes approximately 15h 18m.
The distance between St. Louis and Duncan is 549 miles. The road distance is 655.8 miles.
The best way to get from St. Louis to Duncan without a car is to bus which takes 15h 18m and costs $140 - $230.
It takes approximately 4h 55m to get from St. Louis to Duncan, including transfers.
St. Louis to Duncan bus services, operated by Greyhound USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Duncan is to fly which takes 4h 55m and costs $140 - $700. Alternatively, you can bus, which costs $140 - $230 and takes 15h 18m.
St. Louis to Duncan bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Duncan is 1h ahead of St. Louis. It is currently 12:41 PM in St. Louis and 1:41 PM in Duncan.
What companies run services between St. Louis, MO, USA and Duncan, SC, USA?
Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from St Louis Bus Station to Duncan via Atlanta Bus Station and Greenville in around 15h 18m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $80–460
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $90–480
Flights from Lambert–St. Louis International Airport to Columbia via Reagan Washington
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Columbia via Charlotte
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $80–450
Flights from Lambert–St. Louis International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Columbia via Dallas/Ft.Worth
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Atlanta Bus Station to Greenville
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $23–40
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between St. Louis to Duncan is 656 miles. It takes approximately 11h 6m to drive from St. Louis to Duncan.
There are 127+ hotels available in Duncan.


