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How to get fromSt. Louis to Edisto Islandby plane, bus, or car

Find Transport to Edisto Island

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There are 5 ways to get from St. Louis to Edisto Island by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS)plane plane STL - CHS
    2. Take the bus from Citadel Mall to SC 174 / Indigo Hill Rdbus bus
    7h 51m
    $108–560

  2. Bus, drive

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Savannahbus bus
    3. Drive from Savannah to Edisto Islandcar car
    17h 44m
    $165–283

  3. Drive 831.6 mi

    1. Drive from St. Louis to Edisto Islandcar car 831.6 mi
    14h 48m
    $152–220

  4. Fly to Hilton Head Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Hilton Head Airport (HHH)plane plane STL - HHH
    2. Drive from Hilton Head Airport (HHH) to Edisto Islandcar car
    7h 37m
    $120–528

  5. Bus, drive via Evansville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Savannah Bus Stationbus bus
    4. Take the bus from Bluffton Transfer Center to Seaside Rd at Robert and Clara Trlbus bus 302
    5. Drive from Seaside Rd at Robert and Clara Trl to Edisto Islandcar car
    22h 20m

Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS) flights

Calendar53Weekly Planes
Duration3h 48mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Edisto Island.ExpandLaunch map view
  • Distance: 778.1 mi
  • Duration: 7h 51m

What companies run services between St. Louis, MO, USA and Edisto Island, Charleston County, SC, USA?

There is no direct connection from St. Louis to Edisto Island. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, take the line 11 bus to Rivers Ave / Cosgrove Ave, walk to N. Charleston SuperStop on Cosgrove Ave, take the line 32 bus to Citadel Mall, then take the bus to SC 174 / Indigo Hill Rd. Alternatively, you can take a bus from St Louis Bus Station to Edisto Island via Atlanta and Savannah in around 17h 44m.

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