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How to get fromSt. Louis to Florenceby plane, taxi, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from St. Louis to Florence by plane, taxi, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Huntsville International Airport-Carl T Jones Field, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane STL - HSV
    2. Take the taxi from Huntsville International Airport-Carl T Jones Field (HSV) to Florencetaxi taxi
    6h 26m
    $252–822

  2. Drive 348.5 mi

    cheapest
    1. Drive from St. Louis to Florencecar car 348.5 mi
    7h 8m
    $64–92

  3. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florencebus bus
    19h 40m
    $143–281

  4. Fly to Nashville, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    2. Drive from Nashville-Airport-BNA to Florencecar car
    5h 26m
    $104–638

  5. Fly to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane plane STL - BHM
    2. Drive from Birmingham-Airport-BHM to Florencecar car
    7h 10m
    $144–788

  6. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Florencebus bus Greyhound US0622s
    20h 15m
    $143–268

Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV) flights

Calendar132Weekly Planes
Duration5h 20mAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Florence.ExpandLaunch map view
  • Distance: 422 mi
  • Duration: 6h 26m

What companies run services between St. Louis, MO, USA and Florence, AL, USA?

You can take a bus from St. Louis to Florence via Carbondale Intermodal Station, Atlanta Bus Station, and Florence in around 19h 40m.

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